CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005376
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Inorganic phosphate transporter PHO87 
Protein Synonyms/Alias
  
Gene Name
 PHO87 
Gene Synonyms/Alias
 YCR037C; YCR37C; YCR524 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
89KRKLFGSKTPSGSKRubiquitination[1]
102KRGDSDEKAIDGNNIubiquitination[1, 2, 3, 4, 5]
124DELSPQGKTTSFNKNubiquitination[1]
130GKTTSFNKNFIRKKFubiquitination[1]
315LNRMGFSKITKKSDKubiquitination[1]
340IESEEFFKDTYIFQHubiquitination[5]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] A proteomics approach to understanding protein ubiquitination.
 Peng J, Schwartz D, Elias JE, Thoreen CC, Cheng D, Marsischky G, Roelofs J, Finley D, Gygi SP.
 Nat Biotechnol. 2003 Aug;21(8):921-6. [PMID: 12872131]
 [3] Computational identification of ubiquitylation sites from protein sequences.
 Tung CW, Ho SY.
 BMC Bioinformatics. 2008 Jul 15;9:310. [PMID: 18625080]
 [4] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269]
 [5] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 Involved in the uptake of inorganic phosphate. 
Sequence Annotation
 DOMAIN 1 334 SPX.
 MOD_RES 228 228 Phosphoserine.
 CARBOHYD 162 162 N-linked (GlcNAc...) (Potential).
 CARBOHYD 202 202 N-linked (GlcNAc...) (Potential).
 CARBOHYD 274 274 N-linked (GlcNAc...) (Potential).
 CROSSLNK 102 102 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Complete proteome; Glycoprotein; Isopeptide bond; Membrane; Phosphate transport; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 923 AA 
Protein Sequence
MRFSHFLKYN AVPEWQNHYL DYNELKNLIY TLQTDELKQE TPTGDLNDDA DSQTPGPIAD 60
IESNIAAGEP SSSKRRFTHK LKRKLFGSKT PSGSKRGDSD EKAIDGNNIN EETIELDELS 120
PQGKTTSFNK NFIRKKFFES RSSSVSSEGK TLFSSYDTFV TNLSDEKLKV DDFYKRMEAK 180
FYERFDHLIN DLEKEGIVTR LNETFNPEIQ ALPPLREIIS GTSETHSSNN PFEIHSSNID 240
SELRNRFDYS EEEMDEDDDV DVFADTTDNT ALLNYSQFNI KSQKKSLLKQ TIINLYIDLC 300
QLKSFIELNR MGFSKITKKS DKVLHMNTRQ ELIESEEFFK DTYIFQHETL SSLNSKIAQL 360
IEFYAVLMGQ PGNVDSCKQE LKSYLHDHIV WERSNTWKDM LGLSSQNNDI ITIEDEAEKL 420
MQEKLQIEYF KYPLPKPINL KFTKIENLAV PKLFFGKRAM KIGFIIIVTG VLLGVKTFND 480
PVEHRCMALV ECCAFLWASE AIPLHITGLL VPLLTVLFRV LKDDDGKVMG AAAASTEILG 540
TMWSSTIMIL LAGFTLGEAL SQYNVAKVLA SWLLALAGTK PRNVLLMAMS VVFFLSMWIS 600
NVASPVLTYS LLTPLLDPLD YTSPFAKALV MGVALSADIG GMASPISSPQ NIISMQYLKP 660
YGIGWGQFFA VALPTGILSM LCSWALMILT FKIGKTKLEK FKPIRTRFTI KQYFIIIVTI 720
ATILLWCVES QIESAFGSSG EIAVIPIVLF FGTGLLSTKD FNTFPWSIVV LAMGGIALGK 780
AVSSSGLLVT IARALQKKIQ NDGVFAILCI FGILMLVVGT FVSHTVSAII IIPLVQEVGD 840
KLSDPKAAPI LVFGCALLAS CGMGLASSGF PNVTAISMTD KKGNRWLTVG AFISRGVPAS 900
LLAFVCVITL GYGISSSVLK GST 923 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005315; F:inorganic phosphate transmembrane transporter activity; IGI:SGD.
 GO:0006817; P:phosphate ion transport; IGI:SGD. 
Interpro
 IPR004680; Cit_transptr-like_dom.
 IPR004331; SPX_N. 
Pfam
 PF03600; CitMHS
 PF03105; SPX 
SMART
  
PROSITE
 PS51382; SPX 
PRINTS