CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003967
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ran GTPase-activating protein 1 
Protein Synonyms/Alias
 Protein involved in RNA production/processing 
Gene Name
 RNA1 
Gene Synonyms/Alias
 YMR235C; YM9959.17C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
288FKVFTEVKFPNLHVLacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 GTPase activator for the nuclear Ras-related regulatory protein GSP1 (Ran), converting it to the putatively inactive GDP- bound state. 
Sequence Annotation
 REPEAT 11 39 LRR 1.
 REPEAT 40 67 LRR 2.
 REPEAT 68 101 LRR 3.
 REPEAT 102 133 LRR 4.
 REPEAT 134 166 LRR 5.
 REPEAT 167 197 LRR 6.
 REPEAT 198 226 LRR 7.
 REPEAT 227 256 LRR 8.
 REPEAT 257 285 LRR 9.
 REPEAT 286 315 LRR 10.
 REPEAT 316 346 LRR 11.
 MOD_RES 360 360 Phosphoserine.  
Keyword
 Complete proteome; Cytoplasm; GTPase activation; Leucine-rich repeat; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 407 AA 
Protein Sequence
MATLHFVPQH EEEQVYSISG KALKLTTSDD IKPYLEELAA LKTCTKLDLS GNTIGTEASE 60
ALAKCIAENT QVRESLVEVN FADLYTSRLV DEVVDSLKFL LPVLLKCPHL EIVNLSDNAF 120
GLRTIELLED YIAHAVNIKH LILSNNGMGP FAGERIGKAL FHLAQNKKAA SKPFLETFIC 180
GRNRLENGSA VYLALGLKSH SEGLKVVKLY QNGIRPKGVA TLIHYGLQYL KNLEILDLQD 240
NTFTKHASLI LAKALPTWKD SLFELNLNDC LLKTAGSDEV FKVFTEVKFP NLHVLKFEYN 300
EMAQETIEVS FLPAMEKGNL PELEKLEING NRLDEDSDAL DLLQSKFDDL EVDDFEEVDS 360
EDEEGEDEED EDEDEKLEEI ETERLEKELL EVQVDDLAER LAETEIK 407 
Gene Ontology
 GO:0005829; C:cytosol; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0005098; F:Ran GTPase activator activity; IDA:SGD.
 GO:0006348; P:chromatin silencing at telomere; IMP:SGD.
 GO:0006606; P:protein import into nucleus; IDA:SGD.
 GO:0000054; P:ribosomal subunit export from nucleus; IMP:SGD.
 GO:0006404; P:RNA import into nucleus; IMP:SGD.
 GO:0006407; P:rRNA export from nucleus; IMP:SGD.
 GO:0016072; P:rRNA metabolic process; IMP:SGD.
 GO:0006399; P:tRNA metabolic process; IMP:SGD. 
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PRINTS