UniProt Accession

 ZINT_ECOLI; P76344; Q2MAZ5 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC75039.1; BAE76561.1 

Protein Name

 Metal-binding protein ZinT 

Protein Synonyms/Alias

 Cadmium-induced protein ZinT 

Gene Name

 zinT 

Gene Synonyms/Alias

 yodA; b1973; JW1956 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
39	PLTEVEQKAANGVFD	acetylation	[1]
80	KLDPVFQKKADADKT	acetylation	[1]
88	KADADKTKTFAEIKD	acetylation	[1]
94	TKTFAEIKDYYHKGY	acetylation	[1]
127	NNETTSCKYDYDGYK	acetylation	[1]
134	KYDYDGYKILTYKSG	acetylation	[1]
152	VRYLFECKDPESKAP	acetylation	[1]
160	DPESKAPKYIQFSDH	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2+) over Cd(2+). Contains one high affinity metal binding site, and can bind additional metal ions at other sites. 

Sequence Annotation

 METAL 167 167 Zinc 1.
 METAL 176 176 Zinc 1.
 METAL 176 176 Zinc 2.
 METAL 178 178 Zinc 1.
 METAL 212 212 Zinc 2.
 METAL 216 216 Zinc 2.  

Keyword

 3D-structure; Cadmium; Complete proteome; Cytoplasm; Direct protein sequencing; Metal-binding; Nickel; Periplasm; Reference proteome; Signal; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 216 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:EcoCyc.
 GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoCyc.
 GO:0046870; F:cadmium ion binding; IDA:EcoCyc.
 GO:0008270; F:zinc ion binding; IDA:EcoCyc.
 GO:0034224; P:cellular response to zinc ion starvation; IEP:EcoCyc.
 GO:0046686; P:response to cadmium ion; IEP:EcoCyc. 

Interpro

 IPR012674; Calycin.
 IPR011038; Calycin-like.
 IPR015304; YodA. 

Pfam

 PF09223; YodA 

SMART

  

PROSITE

  

PRINTS