| Tag | Content |
|---|
| CPLM ID | CPLM-015653 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc transporter ZIP14 |
Protein Synonyms/Alias | Factor for adipocyte differentiation 123; FAD-123; Solute carrier family 39 member 14; Zrt- and Irt-like protein 14; ZIP-14 |
Gene Name | Slc39a14 |
Gene Synonyms/Alias | Fad123; Kiaa0062; Zip14 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 273 | QEEGVTEKLQNGDLD | ubiquitination | [1] | | 294 | CNSELDGKAPGTDEK | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Broad-scope metal ion transporter with a preference for zinc uptake. Also mediates cellular uptake of nontransferrin-bound iron. |
Sequence Annotation | MOTIF 248 255 HHHGHXHX-motif.
MOTIF 373 378 XEXPHE-motif.
CARBOHYD 52 52 N-linked (GlcNAc...).
CARBOHYD 75 75 N-linked (GlcNAc...).
CARBOHYD 85 85 N-linked (GlcNAc...).
CARBOHYD 100 100 N-linked (GlcNAc...). |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Glycoprotein; Ion transport; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 489 AA |
Protein Sequence | MKRLHPALPS CLLLVLFGIW RTAPQTHASS AGLPPLSATS FLEDLMDRYG KNDSLTLTQL 60
KSLLDHLHVG VGRDNVSQPK EGPRNLSTCF SSGDLFAAHN LSERSQIGAS EFQEFCPTIL 120
QQLDSQACTS ENQKSEENEQ TEEGKPSAIE VWGYGFLCVT VISLCSLMGA SVVPFMKKTF 180
YKRLLLYFIA LAIGTLYSNA LFQLIPEAFG FNPQDNYVSK SAVVFGGFYL FFFTEKILKM 240
LLKQKNEHHH GHNHFTSETL PSKKDQEEGV TEKLQNGDLD HMIPQHCNSE LDGKAPGTDE 300
KVIVNSMSVQ DLQASQSACY WLKGVRYSDI GTLAWMITLS DGLHNFIDGL AIGASFTVSV 360
FQGISTSVAI LCEEFPHELG DFVILLNAGM SIQQALFFNF LSACCCYLGL AFGILAGSHF 420
SANWIFALAG GMFLYIALAD MFPEMNEVCQ EDEKNDSFLV PFVIQNLGLL TGFSIMLVLT 480
MYSGQIQIG 489 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IEA:Compara. GO:0005794; C:Golgi apparatus; IEA:Compara. GO:0005887; C:integral to plasma membrane; IEA:Compara. GO:0005886; C:plasma membrane; IDA:MGI. GO:0015093; F:ferrous iron transmembrane transporter activity; IDA:MGI. GO:0005385; F:zinc ion transmembrane transporter activity; IDA:MGI. GO:0006882; P:cellular zinc ion homeostasis; IEA:Compara. GO:0071578; P:zinc ion transmembrane import; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |