CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042825
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Synembryn-A 
Protein Synonyms/Alias
  
Gene Name
 RIC8A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
223LHKTHRLKESVAPVLubiquitination[1]
248RPARKFLKAQVLPPLubiquitination[1, 2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 287 AA 
Protein Sequence
XCLCNLVLSS PVAQMLAAEA RLVVKLTERV GLYRERSFPH DVQFFDLRLL FLLTALRTDV 60
RQQLFQELKG VRLLTDTLEL TLGVTPEGNP PPTLLPSQET ERAMEILKVL FNITLDSIKG 120
EVDEHYPESP RKTPGDQEDA ALYRHLGTLL RHCVMIATAG DRTEEFHGHA VNLLGNLPLK 180
CLDVLLTLEP HGDSTEFMGV NMDVIRALLI FLEKRLHKTH RLKESVAPVL SVLTECARMH 240
RPARKFLKAQ VLPPLRDVRT RPEVGEMLRN KLVRLMTHLD TDVKRVA 287 
Gene Ontology
  
Interpro
 IPR019318; Gua_nucleotide_exch_fac_Ric8.
 IPR008376; Synembryn. 
Pfam
 PF10165; Ric8 
SMART
  
PROSITE
  
PRINTS
 PR01802; SYNEMBRYN.