CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031994
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chromodomain-helicase-DNA-binding protein 2 
Protein Synonyms/Alias
 cDNA FLJ53879, highly similar to Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) 
Gene Name
 CHD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
448EDEALIGKKFQNCIDubiquitination[1]
449DEALIGKKFQNCIDSubiquitination[1]
485PRFVALKKQPAYLGGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; DNA-binding; Helicase; Hydrolase; Nucleotide-binding; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 514 AA 
Protein Sequence
MAHKQREDYL NLSPCVFTWY RTFSQLAFDG EKLSHSASEE ASGSDSGSQS ESEQGSDPGS 60
GHGSESNSSS ESSESQSESE SESAGSKSQP VLPEAKEKPA SKKERIADVK KMWEEYPDVY 120
GVRRSNRSRQ EPSRFNIKEE ASSGSESGSP KRRGQRQLKK QEKWKQEPSE DEQEQGTSAE 180
SEPEQKKVKA RRPVPRRTVP KPRVKKQPKT QRGKRKKQDS SDEDDDDDEA PKRQTRRRAA 240
KNVSYKEDDD FETDSDDLIE MTGEGVDEQQ DNSETIEKVL DSRLGKKGAT GASTTVYAIE 300
ANGDPSGDFD TEKDEGEIQY LIKWKGWSYI HSTWESEESL QQQKVKGLKK LENFKKKEDE 360
IKQWLGKVSP EDVEYFNCQQ ELASELNKQY QIVERVIAVK TSKSTLGQTD FPAHSRKPAP 420
SNEPEYLCKW MGLPYSECSW EDEALIGKKF QNCIDSFHSR NNSKTIPTRE CKALKQRPRF 480
VALKKQPAYL GGENLELRDY QLEGLNWLAH SWCK 514 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0004386; F:helicase activity; IEA:UniProtKB-KW. 
Interpro
 IPR023780; Chromo_domain.
 IPR000953; Chromo_domain/shadow.
 IPR016197; Chromodomain-like.
 IPR023779; Chromodomain_CS. 
Pfam
 PF00385; Chromo 
SMART
 SM00298; CHROMO 
PROSITE
 PS00598; CHROMO_1
 PS50013; CHROMO_2 
PRINTS