| Tag | Content |
|---|
| CPLM ID | CPLM-021713 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Solute carrier organic anion transporter family member 2B1 |
Protein Synonyms/Alias | Organic anion transporter moatp1; Solute carrier family 21 member 9 |
Gene Name | Slco2b1 |
Gene Synonyms/Alias | Oatp2b1; Slc21a9 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 296 | PREMPKEKYELHFRQ | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. |
Sequence Annotation | DOMAIN 471 531 Kazal-like.
MOD_RES 21 21 Phosphoserine (By similarity).
CARBOHYD 165 165 N-linked (GlcNAc...) (Potential).
CARBOHYD 255 255 N-linked (GlcNAc...) (Potential).
CARBOHYD 526 526 N-linked (GlcNAc...) (Potential).
CARBOHYD 533 533 N-linked (GlcNAc...) (Potential).
DISULFID 477 504 By similarity.
DISULFID 481 492 By similarity.
DISULFID 483 508 By similarity. |
Keyword | Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; Ion transport; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 682 AA |
Protein Sequence | MPDRSTKATM GAEDIHERKV SMEPRDSHQD AQPRGMFQNI KFFVLCHSIL QLAQLMISGY 60
LKSSISTVEK RFGLSSQTSG LLAAFNEVGN ISLILFVSYF GSRVHRPRMI GCGAILVAVA 120
GLLMALPHFI SEPYRYDHSS PDRSQDFEAS LCLPTTMAPA SALSNDSCSS RTETKHLTMV 180
GIMFTAQTLL GIGGVPIQPF GISYIDDFAH HSNSPLYLGI LFAITMMGPG LAYGLGSLML 240
RLYVDIDRMP EGGINLTTKD PRWVGAWWLG FLISAGLVVL AASPYFFFPR EMPKEKYELH 300
FRQKVLAGGA SIGSKGEELS SQHEPLKKQA GLPQIAPDLT VVQFIKVFPR VLLRTLRHPI 360
FLLVVLSQVC TSSMVAGTAT FLPKFLERQF SITASFANLL LGCLTIPLAI VGIVVGGVLV 420
KRLHLSPMQC SALCLLGSLL CLLLSLPLFF IGCSTHHIAG ITQDLGAQPG PSLFPGCSEP 480
CSCQSDDFNP VCDTSAYVEY TTPCHAGCTG RVVQEALDKS QVFYTNCSCV AGNGTISAGS 540
CESACSRLVL PFILLISLGA AVASITHTPS FMLILRGVKK EDKTLAVGMQ FMLLRVLAWM 600
PSPVIHGSAI DTTCVHWALT CGRRAVCRYY DHDLLRNRFI GLQFFFKSGS LVCFALVLAI 660
LRQQSREAST KATVKSSDLQ EL 682 |
Gene Ontology | GO:0016324; C:apical plasma membrane; IDA:RGD. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0015125; F:bile acid transmembrane transporter activity; IDA:RGD. GO:0015347; F:sodium-independent organic anion transmembrane transporter activity; IDA:RGD. GO:0001889; P:liver development; IEP:RGD. GO:0071718; P:sodium-independent icosanoid transport; IDA:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |