UniProt Accession

 A6NMH0_HUMAN; A6NMH0 

Genbank Protein ID

 AC008501; AC008779; AC010250; AC113373 

Genbank Nucleotide ID

  

Protein Name

 Probable E3 ubiquitin-protein ligase MYCBP2 

Protein Synonyms/Alias

  

Gene Name

 PAM 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
96	QCFKTDTKEFVREIK	ubiquitination	[1]
199	LEHRSVKKAGIEVQE	ubiquitination	[1]
278	KSRAFGGKGSGGLNL	ubiquitination	[2, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 335 AA 

Protein Sequence

Gene Ontology

 GO:0016020; C:membrane; IEA:InterPro.
 GO:0005507; F:copper ion binding; IEA:InterPro.
 GO:0004504; F:peptidylglycine monooxygenase activity; IEA:InterPro.
 GO:0006518; P:peptide metabolic process; IEA:InterPro. 

Interpro

 IPR011042; 6-blade_b-propeller_TolB-like.
 IPR001258; NHL_repeat.
 IPR013017; NHL_repeat_subgr.
 IPR000720; Pep_amidat_mOase. 

Pfam

 PF01436; NHL 

SMART

  

PROSITE

 PS51125; NHL 

PRINTS

 PR00790; PAMONOXGNASE.