CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034854
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein LOC100909750 
Protein Synonyms/Alias
  
Gene Name
 LOC100909750 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
744RDLPSAGKQFDSSTFacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; SH3 domain; Transferase; Tyrosine-protein kinase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1124 AA 
Protein Sequence
MLEICLKLVG CKSKKGLSSS SSCYLEEALQ RPVASDFEPQ GLSEAARWNS KENLLAGPSE 60
NDPNLFVALY DFVASGDNTL SITKGEKLRV LGYNHNGEWC EAQTKNGQGW VPSNYITPVN 120
SLEKHSWYHG PVSRNAAEYL LSSGINGSFL VRESESSPGQ RSISLRYEGR VYHYRINTAS 180
DGKLYVSSES RFNTLAELVH HHSTVADGLI TTLHYPAPKR NKPTIYGVSP NYDKWEMERT 240
DITMKHKLGG GQYGEVYEGV WKKYSLTVAV KTLKEDTMEV EEFLKEAAVM KEIKHPNLVQ 300
LLGVCTREPP FYIITEFMTY GNLLDYLREC NRQEVSAVVL LYMATQISSA MEYLEKKNFI 360
HRDLAARNCL VGENHLVKVA DFGLSRLMTG DTYTAHAGAK FPIKWTAPES LAYNKFSIKS 420
DVWAFGVLLW EIATYGMSPY PGIDLSQVYE LLEKDYRMER PEGCPEKVYE LMRACWQWNP 480
SDRPSFAEIH QAFETMFQES SISDEVEKEL GKRGMRGAAG STLQAPELPT KTRTCRKTAE 540
QKDAPDALEL LHTKGLGESD ALDSEPAVSP LLPRKERGPP DGSLNEDERL LPKDKKTNLF 600
SALIKKKKKM APTPPKRSSS FREMDGQSER RGASEDDGRE ISNGPPALTS DAVEPTKSPK 660
ASNGAGVPNG AFREPGNSGF RSPHVWKKSS TLTSSRLAAA EEESGLSSSK RFLRSCSASC 720
MPHGVRDTEW RSVTLPRDLP SAGKQFDSST FGGHKSEKPA LPRKRTSESR SEQVAKSTAT 780
PPPRLVKKTE EAAEDVFKDT ESSPGSSPPS LTPKLLRRQV PASPSSGPSH KDEATKGNAS 840
GMGTPATAEP AAPSNKAGLS KASSEEPRAR RHKHSSESPG RDKGRLSKLK PAPPPPPSST 900
GKAGKPAQSP SQDVAGEAGG ATKTKCTSLS VDAVNSDPTK AGQPGEGLRK SVPPSVPKPQ 960
SATKPPGTPT SPVSTPSTAP APSPLAGDQQ PSSAAFIPLI STRVSLRKTR QPPERIASGT 1020
ITKGVVLDST EALCLAISRN SEQMASHSAV LEAGKNLYTF CVSYVDSIQQ MRNKFAFREA 1080
INKLESNLRE LQICPATASS GPAATQDFSK LLSSVKEISD IVRR 1124 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:InterPro. 
Interpro
 IPR015015; F-actin_binding.
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
 IPR000980; SH2.
 IPR001452; SH3_domain.
 IPR008266; Tyr_kinase_AS.
 IPR020635; Tyr_kinase_cat_dom. 
Pfam
 PF08919; F_actin_bind
 PF07714; Pkinase_Tyr
 PF00017; SH2
 PF00018; SH3_1 
SMART
 SM00808; FABD
 SM00252; SH2
 SM00326; SH3
 SM00219; TyrKc 
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00109; PROTEIN_KINASE_TYR
 PS50001; SH2
 PS50002; SH3 
PRINTS
 PR00401; SH2DOMAIN.
 PR00109; TYRKINASE.