| Tag | Content |
|---|
| CPLM ID | CPLM-002092 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tubulin alpha-1B chain |
Protein Synonyms/Alias | Tubulin alpha-N chain |
Gene Name | ALTBN |
Gene Synonyms/Alias | ALTB1 |
Created Date | July 27, 2013 |
Organism | Physarum polycephalum (Slime mold) |
NCBI Taxa ID | 5791 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 40 | DGQMPSDKSVGGGDD | acetylation | [1] |
|
Reference | [1] Recognition of specific Physarum alpha-tubulin isotypes by a monoclonal antibody. Sequence heterogeneity around the acetylation site at lysine 40. Walden PD, Blindt AB, Birkett CR, Cox RA, Gull K. Eur J Biochem. 1989 Nov 6;185(2):383-9. [ PMID: 2479555] |
Functional Description | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
Sequence Annotation | NP_BIND 142 148 GTP (Potential).
MOD_RES 40 40 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Cytoplasm; Cytoskeleton; GTP-binding; Microtubule; Nucleotide-binding; Nucleus. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 449 AA |
Protein Sequence | MREIISIHIG QAGAQVGNAC WELYCLEHGI NPDGQMPSDK SVGGGDDAFN TFFSETSSGK 60
HVPRAIYLDL EPTVIDEIRT GTYRQLFHPE QLITGKEDAA NNYARGHYTV GKEIVDLCLD 120
RVRKLADQCS GLQGFLVFHS VGGGTGSGFG SLLLERLSVD YGKKSKLDFC VYPSPQVSTA 180
VVEPYNSVLS THGLLEHTDV AFMLDNEAIY DLCKKSLDID RPSYANLNRL VAQVISSLTT 240
SLRFDGALNV DINEFQTNLV PYPRIHFMLA SYAPVISAEK AFHEQLSVAE LTNTVFEPSS 300
MMAKCDPRHG KYMACCLMYR GDVVPKDVTA AVAVIKTKRT IQFVDWCPTG FKCGINYQAP 360
SVVPGGDLAK VQRALCMISN TTAIAEVFSR IDHKFDLMYA KRAFVHWYVG EGMEEGEFSE 420
AREDLAALEK DYEEVGAETV GDDEAEEEM 449 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |