| Tag | Content |
|---|
| CPLM ID | CPLM-022466 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Leucine-rich repeat transmembrane protein FLRT3 |
Protein Synonyms/Alias | Fibronectin-like domain-containing leucine-rich transmembrane protein 3 |
Gene Name | FLRT3 |
Gene Synonyms/Alias | KIAA1469; UNQ856/PRO1865 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 84 | SDLKNLLKVERIYLY | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May have a function in cell adhesion and/or receptor signaling. |
Sequence Annotation | DOMAIN 29 58 LRRNT.
REPEAT 59 80 LRR 1.
REPEAT 84 104 LRR 2.
REPEAT 105 126 LRR 3.
REPEAT 129 150 LRR 4.
REPEAT 155 175 LRR 5.
REPEAT 176 197 LRR 6.
REPEAT 200 220 LRR 7.
REPEAT 226 247 LRR 8.
REPEAT 248 269 LRR 9.
REPEAT 272 293 LRR 10.
DOMAIN 305 357 LRRCT.
DOMAIN 406 501 Fibronectin type-III.
CARBOHYD 226 226 N-linked (GlcNAc...) (Potential).
CARBOHYD 282 282 N-linked (GlcNAc...) (Potential).
CARBOHYD 296 296 N-linked (GlcNAc...) (Potential). |
Keyword | Cell adhesion; Complete proteome; Glycoprotein; Leucine-rich repeat; Membrane; Polymorphism; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 649 AA |
Protein Sequence | MISAAWSIFL IGTKIGLFLQ VAPLSVMAKS CPSVCRCDAG FIYCNDRFLT SIPTGIPEDA 60
TTLYLQNNQI NNAGIPSDLK NLLKVERIYL YHNSLDEFPT NLPKYVKELH LQENNIRTIT 120
YDSLSKIPYL EELHLDDNSV SAVSIEEGAF RDSNYLRLLF LSRNHLSTIP WGLPRTIEEL 180
RLDDNRISTI SSPSLQGLTS LKRLVLDGNL LNNHGLGDKV FFNLVNLTEL SLVRNSLTAA 240
PVNLPGTNLR KLYLQDNHIN RVPPNAFSYL RQLYRLDMSN NNLSNLPQGI FDDLDNITQL 300
ILRNNPWYCG CKMKWVRDWL QSLPVKVNVR GLMCQAPEKV RGMAIKDLNA ELFDCKDSGI 360
VSTIQITTAI PNTVYPAQGQ WPAPVTKQPD IKNPKLTKDH QTTGSPSRKT ITITVKSVTS 420
DTIHISWKLA LPMTALRLSW LKLGHSPAFG SITETIVTGE RSEYLVTALE PDSPYKVCMV 480
PMETSNLYLF DETPVCIETE TAPLRMYNPT TTLNREQEKE PYKNPNLPLA AIIGGAVALV 540
TIALLALVCW YVHRNGSLFS RNCAYSKGRR RKDDYAEAGT KKDNSILEIR ETSFQMLPIS 600
NEPISKEEFV IHTIFPPNGM NLYKNNHSES SSNRSYRDSG IPDSDHSHS 649 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; NAS:UniProtKB. GO:0005578; C:proteinaceous extracellular matrix; NAS:UniProtKB. GO:0030674; F:protein binding, bridging; NAS:UniProtKB. GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB. GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |