CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026186
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG68069 
Protein Synonyms/Alias
 Nucleophosmin 1 
Gene Name
 Npm1 
Gene Synonyms/Alias
 mCG_68069 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
32ADKDYHFKVDNDENEubiquitination[1]
54VSLGAGAKDELHIVEubiquitination[1]
141KLLGMSGKRSAPGGGubiquitination[1]
237EKTPKTPKGPSSVEDubiquitination[1]
261EKGGSLPKVEAKFINubiquitination[1]
265SLPKVEAKFINYVKNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 292 AA 
Protein Sequence
MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV 60
EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE 120
EDAESEDEDE EDVKLLGMSG KRSAPGGGNK VPQKKVKLDE DDEDDDEDDE DDEDDDDDDF 180
DEEETEEKVP VKKSVRDTPA KNAQKSNQNG KDLKPSTPRS KGQESFKKQE KTPKTPKGPS 240
SVEDIKAKMQ ASIEKGGSLP KVEAKFINYV KNCFRMTDQE AIQDLWQWRK SL 292 
Gene Ontology
 GO:0005813; C:centrosome; IDA:MGI.
 GO:0005829; C:cytosol; IDA:MGI.
 GO:0001652; C:granular component; IDA:MGI.
 GO:0015934; C:large ribosomal subunit; IDA:MGI.
 GO:0016607; C:nuclear speck; IDA:MGI.
 GO:0015935; C:small ribosomal subunit; IDA:MGI.
 GO:0043023; F:ribosomal large subunit binding; ISO:MGI.
 GO:0043024; F:ribosomal small subunit binding; ISO:MGI.
 GO:0019843; F:rRNA binding; IDA:MGI.
 GO:0016049; P:cell growth; IDA:MGI.
 GO:0006884; P:cell volume homeostasis; IDA:MGI.
 GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:MGI.
 GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
 GO:0031328; P:positive regulation of cellular biosynthetic process; IDA:MGI.
 GO:0010825; P:positive regulation of centrosome duplication; IGI:MGI.
 GO:0045860; P:positive regulation of protein kinase activity; IDA:MGI.
 GO:0008104; P:protein localization; IMP:MGI.
 GO:0051259; P:protein oligomerization; ISO:MGI.
 GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; IGI:MGI.
 GO:0042273; P:ribosomal large subunit biogenesis; IMP:MGI.
 GO:0000055; P:ribosomal large subunit export from nucleus; IMP:MGI.
 GO:0042274; P:ribosomal small subunit biogenesis; IMP:MGI.
 GO:0000056; P:ribosomal small subunit export from nucleus; IDA:MGI.
 GO:0006407; P:rRNA export from nucleus; IDA:MGI. 
Interpro
 IPR004301; Nucleoplasmin.
 IPR024057; Nucleoplasmin_core_dom. 
Pfam
  
SMART
  
PROSITE
  
PRINTS