CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025760
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Alanine aminotransferase 1 
Protein Synonyms/Alias
 Glutamic pyruvic transaminase 1, soluble, isoform CRA_c 
Gene Name
 Gpt 
Gene Synonyms/Alias
 Alt1; Gpt1; mCG_23646 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
57QELRQGVKKPFTEVIubiquitination[1]
58ELRQGVKKPFTEVIRubiquitination[1]
105PDFPEDAKRRAERILubiquitination[1]
291SQFHSFKKVLTEMGPubiquitination[1]
338NMDAEVQKQMAKLMSubiquitination[1]
342EVQKQMAKLMSVRLCubiquitination[1]
373TPSEPSFKQFQAERQubiquitination[1]
389VLAELAAKAKLTEQVubiquitination[1]
391AELAAKAKLTEQVFNubiquitination[1]
423PQIQLPLKAVQRAQDubiquitination[1]
476TILPPMEKLRVLLEKubiquitination[1]
483KLRVLLEKLRHFHAKubiquitination[1]
490KLRHFHAKFTHEYS*ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminotransferase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 496 AA 
Protein Sequence
MASQRNDRIQ ASRNGLKGKV LTLDTMNPCV RRVEYAVRGP IVQRALELEQ ELRQGVKKPF 60
TEVIRANIGD AQAMGQRPIT FFRQVLALCV YPNLLSSPDF PEDAKRRAER ILQACGGHSL 120
GAYSISSGIQ PIREDVAQYI ERRDGGIPAD PNNIFLSTGA SDAIVTMLKL LVAGEGRART 180
GVLIPIPQYP LYSAALAELD AVQVDYYLDE ERAWALDIAE LRRALCQARD RCCPRVLCVI 240
NPGNPTGQVQ TRECIEAVIR FAFEEGLFLM ADEVYQDNVY AEGSQFHSFK KVLTEMGPPY 300
ATQQELASFH SVSKGYMGEC GFRGGYVEVV NMDAEVQKQM AKLMSVRLCP PVPGQALMGM 360
VVSPPTPSEP SFKQFQAERQ EVLAELAAKA KLTEQVFNEA PGIRCNPVQG AMYSFPQIQL 420
PLKAVQRAQD LGLAPDMFFC LCLLEETGIC VVPGSGFGQQ EGTYHFRMTI LPPMEKLRVL 480
LEKLRHFHAK FTHEYS 496 
Gene Ontology
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
 GO:0009058; P:biosynthetic process; IEA:InterPro. 
Interpro
 IPR004839; Aminotransferase_I/II.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 
Pfam
 PF00155; Aminotran_1_2 
SMART
  
PROSITE
  
PRINTS