CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013702
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 G-protein coupled receptor-associated sorting protein 1 
Protein Synonyms/Alias
 GASP-1 
Gene Name
 GPRASP1 
Gene Synonyms/Alias
 GASP; KIAA0443 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
39VPLVVRPKVRTQAQIubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
 May modulate lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes. 
Sequence Annotation
 REGION 899 1395 OPRD1-binding.  
Keyword
 Complete proteome; Cytoplasm; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1395 AA 
Protein Sequence
MTGAEIESGA QVKPEKKPGE EVVGGAEIEN DVPLVVRPKV RTQAQIMPGA RPKNKSKVMP 60
GASTKVETSA VGGARPKSKA KAIPVSRFKE EAQMWAQPRF GAERLSKTER NSQTNIIASP 120
LVSTDSVLVA KTKYLSEDRE LVNTDTESFP RRKAHYQAGF QPSFRSKEET NMGSWCCPRP 180
TSKQEASPNS DFKWVDKSVS SLFWSGDEVT AKFHPGNRVK DSNRSMHMAN QEANTMSRSQ 240
TNQELYIASS SGSEDESVKT PWFWARDKTN TWSGPREDPN SRSRFRSKKE VYVESSSGSE 300
HEDHLESWFG AGKEAKFRSK MRAGKEANNR ARHRAKREAC IDFMPGSIDV IKKESCFWPE 360
ENANTFSRPM IKKEARARAM TKEEAKTKAR ARAKQEARSE EEALIGTWFW ATDESSMADE 420
ASIESSLQVE DESIIGSWFW TEEEASMGTG ASSKSRPRTD GERIGDSLFG AREKTSMKTG 480
AEATSESILA ADDEQVIIGS WFWAGEEVNQ EAEEETIFGS WFWVIDAASV ESGVGVSCES 540
RTRSEEEEVI GPWFWSGEQV DIEAGIGEEA RPGAEEETIF GSWFWAENQT YMDCRAETSC 600
DTMQGAEEEE PIIGSWFWTR VEACVEGDVN SKSSLEDKEE AMIPCFGAKE EVSMKHGTGV 660
RCRFMAGAEE TNNKSCFWAE KEPCMYPAGG GSWKSRPEEE EDIVNSWFWS RKYTKPEAII 720
GSWLWATEES NIDGTGEKAK LLTEEETIIN SWFWKEDEAI SEATDREESR PEAEEGDIIG 780
SWFWAGEEDR LEPAAETREE DRLAAEKEGI VGSWFGAREE TIRREAGSCS KSSPKAEEEE 840
VIIGSWFWEE EASPEAVAGV GFESKPGTEE EEITVGSWFW PEEEASIQAG SQAVEEMESE 900
TEEETIFGSW FWDGKEVSEE AGPCCVSKPE DDEEMIVESW FWSRDKAIKE TGTVATCESK 960
PENEEGAIVG SWFEAEDEVD NRTDNGSNCG SRTLADEDEA IVGSWFWAGD EAHFESNPSP 1020
VFRAICRSTC SVEQEPDPSR RPQSWEEVTV QFKPGPWGRV GFPSISPFRF PKEAASLFCE 1080
MFGGKPRNMV LSPEGEDQES LLQPDQPSPE FPFQYDPSYR SVQEIREHLR AKESTEPESS 1140
SCNCIQCELK IGSEEFEELL LLMEKIRDPF IHEISKIAMG MRSASQFTRD FIRDSGVVSL 1200
IETLLNYPSS RVRTSFLENM IRMAPPYPNL NIIQTYICKV CEETLAYSVD SPEQLSGIRM 1260
IRHLTTTTDY HTLVANYMSG FLSLLATGNA KTRFHVLKML LNLSENLFMT KELLSAEAVS 1320
EFIGLFNREE TNDNIQIVLA IFENIGNNIK KETVFSDDDF NIEPLISAFH KVEKFAKELQ 1380
GKTDNQNDPE GDQEN 1395 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. 
Interpro
 IPR011989; ARM-like.
 IPR006911; ARM-rpt_dom.
 IPR016024; ARM-type_fold. 
Pfam
 PF04826; Arm_2 
SMART
  
PROSITE
  
PRINTS