CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019206
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein SAAL1 
Protein Synonyms/Alias
  
Gene Name
 SAAL1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
209KVGEVVDKLFDLDEKubiquitination[1, 2, 3, 4, 5]
382ESNTEETKRTDLTQDubiquitination[3]
Reference
 [1] Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.
 Danielsen JM, Sylvestersen KB, Bekker-Jensen S, Szklarczyk D, Poulsen JW, Horn H, Jensen LJ, Mailand N, Nielsen ML.
 Mol Cell Proteomics. 2011 Mar;10(3):M110.003590. [PMID: 21139048]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [5] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
 MOD_RES 6 6 Phosphoserine (By similarity).
 MOD_RES 378 378 Phosphothreonine (By similarity).
 MOD_RES 387 387 Phosphothreonine.  
Keyword
 Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 474 AA 
Protein Sequence
MDRNPSPPPP GRDKEEEEEV AGGDCIGSTV YSKHWLFGVL SGLIQIVSPE NTKSSSDDEE 60
QLTELDEEME NEICRVWDMS MDEDVALFLQ EFNAPDIFMG VLAKSKCPRL REICVGILGN 120
MACFQEICVS ISSDKNLGQV LLHCLYDSDP PTLLETSRLL LTCLSQAEVA SVWVERIQEH 180
PAIYDSICFI MSSSTNVDLL VKVGEVVDKL FDLDEKLMLE WVRNGAAQPL DQPQEESEEQ 240
PVFRLVPCIL EAAKQVRSEN PEWLDVYMHI LQLLTTVDDG IQAIVHCPDT GKDIWNLLFD 300
LVCHEFCQSD DPPIILQEQK TVLASVFSVL SAIYASQTEQ EYLKIEKVDL PLIDSLIRVL 360
QNMEQCQKKP ENSAESNTEE TKRTDLTQDD FHLKILKDIL CEFLSNIFQA LTKETVAQGV 420
KEGQLSKQKC SSAFQNLLPF YSPVVEDFIK ILREVDKALA DDLEKNFPSL KVQT 474 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:InterPro.
 GO:0006953; P:acute-phase response; IEA:InterPro. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR000096; Serum_amyloid_A. 
Pfam
  
SMART
  
PROSITE
  
PRINTS