CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035093
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Nardilysin 
Protein Synonyms/Alias
  
Gene Name
 Nrd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1152SDLVSWFKAHRGPGSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1229 AA 
Protein Sequence
MLRRVAVAAV FATGRKLRCE AGRELTAVGR IEARGLCEES AKPFPTLTMP GRNKAKSTCS 60
CPDLQPNGQD LGESGRVARL GADESEEEGR SLSNVGDPEI IKSPSDPKQY RYIKLQNGLQ 120
ALLISDLSNV EGKTGNATDE EEEEEEEEEE GEEEEEEEED DDDDDDEDSG AEIQDDDEEG 180
FDDEEEFDDD EHDDDDLDNE ENELEELEER VEARKKTTEK QQSQNLFLLW SKLTDRLWFK 240
SSYSKMSSTL LVETRNLYGV VGAESRSAPV EHLAGWQVEE QQGETDTVLS AAALCVGVGS 300
FADPDDLPGL AHFLEHMVFM GSLKYPDENG FDAFLKKHGG SDNASTDCER TVFQFDVQRK 360
YFKEALDRWA QFFIHPLMIR DAIDREVEAV DSEYQLARPS DANRKEMLFG SLARPGHPMG 420
KFFWGNAETL KHEPKKNNID THARLREFWM RYYSAHYMTL VVQSKETLDT LEKWVTEIFS 480
QIPNNGLPKP NFSHLTDPFD TPAFNKLYRV VPIRKIHALT ITWALPPQQQ HYRVKPLHYI 540
SWLVGHEGKG SILSYLRKKC WALALFGGNG ETGFEQNSTY SVFSISITLT DEGYEHFYEV 600
AHTVFQYLKM LQKLGPEKRV FEEIQKIEDN EFHYQEQTDP VEYVENMCEN MQLYPRQDFL 660
TGDQLLFEYK PEVIAEALNQ LVPQKANLVL LSGANEGRCD LKEKWFGTQY SIEDIENSWT 720
ELWKSNFDLN SDLHLPAENK YIATDFTLKA FDCPETEYPA KIVNTPQGCL WYKKDNKFKI 780
PKAYIRFHLI SPLIQKSAAN VVLFDIFVNI LTHNLAEPAY EADVAQLEYK LVAGEHGLII 840
RVKGFNHKLP LLFQLIIDYL TEFSSTPAVF TMITEQLKKT YFNILIKPET LAKDVRLLIL 900
EYSRWSMIDK YRALMDGLSL ESLLNFVKDF KSQLFVEGLV QGNVTSTESM DFLRYVVDKL 960
NFVPLEREMP VQFQVVELPS GHHLCKVRAL NKGDANSEVT VYYQSGTRSL REYTLMELLV 1020
MHMEEPCFDF LRTKQTLGYH VYPTCRNTSG ILGFSVTVGT QATKYNSETV DKKIEEFLSS 1080
FEEKIENLTE DAFNTQVTAL IKLKECEDTH LGEEVDRNWN EVVTQQYLFD RLAHEIEALK 1140
SFSKSDLVSW FKAHRGPGSK MLSVHVVGYG KYELEEDGAP VCEDPNSREG MQLIYLPPSP 1200
LLAESTTPIT DIRAFTATLS LFPYHKIVK 1229 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR011249; Metalloenz_LuxS/M16.
 IPR011237; Pept_M16_dom.
 IPR011765; Pept_M16_N.
 IPR001431; Pept_M16_Zn_BS.
 IPR007863; Peptidase_M16_C. 
Pfam
 PF00675; Peptidase_M16
 PF05193; Peptidase_M16_C 
SMART
  
PROSITE
 PS00143; INSULINASE 
PRINTS