CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010624
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Rho-related GTP-binding protein RhoD 
Protein Synonyms/Alias
  
Gene Name
 Rhod 
Gene Synonyms/Alias
 Arhd; Rhom 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
137KIDLRKDKVLVNNLRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton. 
Sequence Annotation
 NP_BIND 24 31 GTP (By similarity).
 NP_BIND 71 75 GTP (By similarity).
 NP_BIND 129 132 GTP (By similarity).
 MOTIF 46 54 Effector region (Potential).
 MOD_RES 207 207 Cysteine methyl ester (By similarity).
 LIPID 207 207 S-geranylgeranyl cysteine (By  
Keyword
 Cell membrane; Complete proteome; Endosome; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Prenylation; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 210 AA 
Protein Sequence
MNASQVAGEE APQSGHSVKV VLVGDGGCGK TSLMMVFAKG AFPESYSPTV FERYNATLQM 60
KGKPVHLQIW DTAGQDDYDR LRPLFYPDAN VLLLCFDVTN PNSFDNVSNR WYPEVTHFCK 120
GVPIIVVGCK IDLRKDKVLV NNLRKKRLEP VTYHRGHDMA RSVGAVAYLE CSARLHDNVE 180
AVFQEAAEVA LSSRRHNFWR RITQNCCLAT 210 
Gene Ontology
 GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IDA:MGI.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003578; Small_GTPase_Rho. 
Pfam
 PF00071; Ras 
SMART
 SM00174; RHO 
PROSITE
 PS51420; RHO 
PRINTS
 PR00449; RASTRNSFRMNG.