| Tag | Content |
|---|
| CPLM ID | CPLM-002984 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glycerol-3-phosphate acyltransferase |
Protein Synonyms/Alias | GPAT |
Gene Name | plsB |
Gene Synonyms/Alias | b4041; JW4001 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 98 | VFTYYTPKEESIKLF | acetylation | [1] | | 103 | TPKEESIKLFHDYLD | acetylation | [1] | | 184 | ADEHGTDKTIAQKLA | acetylation | [1] | | 189 | TDKTIAQKLARVARM | acetylation | [1] | | 219 | ARQDLFNKLLASRAI | acetylation | [1] | | 357 | FFIRRTFKGNKLYST | acetylation | [1] | | 360 | RRTFKGNKLYSTVFR | acetylation | [1] | | 398 | TGRLLDPKTGTLSMT | acetylation | [1] | | 437 | MEVGTYAKELRGATK | acetylation | [1] | | 589 | MNKFEVEKDTIGDII | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor. |
Sequence Annotation | MOTIF 306 311 HXXXXD motif. |
Keyword | Acyltransferase; Cell inner membrane; Cell membrane; Complete proteome; Direct protein sequencing; Lipid biosynthesis; Lipid metabolism; Membrane; Phospholipid biosynthesis; Phospholipid metabolism; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 807 AA |
Protein Sequence | MSGWPRIYYK LLNLPLSILV KSKSIPADPA PELGLDTSRP IMYVLPYNSK ADLLTLRAQC 60
LAHDLPDPLE PLEIDGTLLP RYVFIHGGPR VFTYYTPKEE SIKLFHDYLD LHRSNPNLDV 120
QMVPVSVMFG RAPGREKGEV NPPLRMLNGV QKFFAVLWLG RDSFVRFSPS VSLRRMADEH 180
GTDKTIAQKL ARVARMHFAR QRLAAVGPRL PARQDLFNKL LASRAIAKAV EDEARSKKIS 240
HEKAQQNAIA LMEEIAANFS YEMIRLTDRI LGFTWNRLYQ GINVHNAERV RQLAHDGHEL 300
VYVPCHRSHM DYLLLSYVLY HQGLVPPHIA AGINLNFWPA GPIFRRLGAF FIRRTFKGNK 360
LYSTVFREYL GELFSRGYSV EYFVEGGRSR TGRLLDPKTG TLSMTIQAML RGGTRPITLI 420
PIYIGYEHVM EVGTYAKELR GATKEKESLP QMLRGLSKLR NLGQGYVNFG EPMPLMTYLN 480
QHVPDWRESI DPIEAVRPAW LTPTVNNIAA DLMVRINNAG AANAMNLCCT ALLASRQRSL 540
TREQLTEQLN CYLDLMRNVP YSTDSTVPSA SASELIDHAL QMNKFEVEKD TIGDIIILPR 600
EQAVLMTYYR NNIAHMLVLP SLMAAIVTQH RHISRDVLME HVNVLYPMLK AELFLRWDRD 660
ELPDVIDALA NEMQRQGLIT LQDDELHINP AHSRTLQLLA AGARETLQRY AITFWLLSAN 720
PSINRGTLEK ESRTVAQRLS VLHGINAPEF FDKAVFSSLV LTLRDEGYIS DSGDAEPAET 780
MKVYQLLAEL ITSDVRLTIE SATQGEG 807 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; IDA:EcoliWiki. GO:0004366; F:glycerol-3-phosphate O-acyltransferase activity; IMP:EcoliWiki. GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway. GO:0006631; P:fatty acid metabolic process; IMP:EcoliWiki. GO:0008654; P:phospholipid biosynthetic process; IMP:EcoliWiki. |
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