CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010613
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative short-chain type dehydrogenase/reductase Rv0148 
Protein Synonyms/Alias
  
Gene Name
 Rv0148 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mycobacterium tuberculosis 
NCBI Taxa ID
 1773 
Lysine Modification
Position
Peptide
Type
References
280ITDLSGAKIAGFKL*pupylation[1]
Reference
 [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036] 
Functional Description
  
Sequence Annotation
 NP_BIND 11 35 NAD or NADP (By similarity).
 ACT_SITE 164 164 Proton acceptor (By similarity).
 BINDING 151 151 Substrate (By similarity).
 CROSSLNK 280 280 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Complete proteome; Isopeptide bond; Oxidoreductase; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 286 AA 
Protein Sequence
MPGVQDRVIV VTGAGGGLGR EYALTLAGEG ASVVVNDLGG ARDGTGAGSA MADEVVAEIR 60
DKGGRAVANY DSVATEDGAA NIIKTALDEF GAVHGVVSNA GILRDGTFHK MSFENWDAVL 120
KVHLYGGYHV LRAAWPHFRE QSYGRVVVAT STSGLFGNFG QTNYGAAKLG LVGLINTLAL 180
EGAKYNIHAN ALAPIAATRM TQDILPPEVL EKLTPEFVAP VVAYLCTEEC ADNASVYVVG 240
GGKVQRVALF GNDGANFDKP PSVQDVAARW AEITDLSGAK IAGFKL 286 
Gene Ontology
 GO:0005618; C:cell wall; IDA:MTBBASE.
 GO:0005886; C:plasma membrane; IDA:MTBBASE.
 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
 GO:0070490; P:protein pupylation; IDA:UniProtKB. 
Interpro
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 
Pfam
 PF00106; adh_short 
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.