CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028812
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transcription initiation factor TFIID subunit 3 
Protein Synonyms/Alias
  
Gene Name
 Taf3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
113IAKPLETKSFTPKTKacetylation[1, 2]
198PSAMVVEKTVKETIPacetylation[1]
626QDKIVISKVVPAPEAacetylation[1, 2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 779 AA 
Protein Sequence
MQVPLEEDDE MEEEEVINDE NFLGKRPLDS PEVEEMPSMK RPRLLSTKGD SLDVVLLEAR 60
EPLSSINPQK TPPVLSPVRV QDRADLAPPS PQPPMLAPFA KSQLPIAKPL ETKSFTPKTK 120
TKASSPGQKT KSPKAALSPA RLGSPIRSPK TIPKEKKSPG RSKSPKSPKS PKIVAHVPQT 180
PVRPETPNRT PSAMVVEKTV KETIPVMKPT QTPPEVVKLN IEMQPKKPVV TDKTIDDSID 240
AVIARACAER EPDPFEFSSG SESEGDTFTS PKRISGSECA TPKASTSSNN FTKSLATPLP 300
LSSGTSSSDN SWTMDASIDE VVRKAKLGAP SNMPPTFPYI SSPSISPPTP EPLHKGYEEK 360
AKLPSSVDVK KKLKKELKTK LKKKEKQRDR ERERERNKER SKEKDKMRER EKEKEAGKEL 420
KYPWRELMKD EDSDPYKFKI KEFEDIDAAK VRLKDGIVRR EREKHKDKKK DRERSKREKD 480
KRERERLKEK NREDKIKAPP TQLVLPPKEM ALPLFSPSAV RVPAMLPAFS PMLPEKLFEE 540
KEKPKEKERK KDKKEKKKKK EKEKEKEKKE REREKERRER EKREKEKEKH KHEKIKVEPV 600
IPAPSPVIPR LTLRVGAGQD KIVISKVVPA PEAKPAPSLN RPKTPPPAPV PIPVRVSPTP 660
LQPPLLTQAA VCPALMPSPA PALSGIGSAK APVRSVVTET VSTYVIRDEW GNQIWICPGC 720
NKPDDGSPMI GCDDCDDWYH WPCVGIMAAP PEEMQWFCPK CANKIKKDKK HKKRKHRAH 779 
Gene Ontology
 GO:0005669; C:transcription factor TFIID complex; ISA:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0051457; P:maintenance of protein location in nucleus; IEA:Compara.
 GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:MGI.
 GO:0006366; P:transcription from RNA polymerase II promoter; TAS:MGI. 
Interpro
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF00628; PHD 
SMART
 SM00249; PHD 
PROSITE
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 
PRINTS