UniProt Accession

 MAGF1_HUMAN; Q9HAY2; Q9H215 

Genbank Protein ID

 AF295378; AC107294; BC010056; AF320910 

Genbank Nucleotide ID

 AAG30208.1; AAH10056.1; AAG38606.1 

Protein Name

 Melanoma-associated antigen F1 

Protein Synonyms/Alias

 MAGE-F1 antigen 

Gene Name

 MAGEF1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
38	TASQERPKEELGAGR	ubiquitination	[1]
65	GARALAAKALARRRA	ubiquitination	[2]
104	ITRSEMVKYVIGDLK	ubiquitination	[1, 2]
150	YILINKLKPLEEEEE	ubiquitination	[1]
251	RSNLEISKMEVLGFV	ubiquitination	[1, 2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. 

Sequence Annotation

 DOMAIN 76 277 MAGE.  

Keyword

 Complete proteome; Polymorphism; Reference proteome; Tumor antigen; Ubl conjugation pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 307 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR002190; MAGE. 

Pfam

 PF01454; MAGE 

SMART

  

PROSITE

 PS50838; MAGE 

PRINTS