CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032454
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tcf20 protein 
Protein Synonyms/Alias
 Transcription factor 20 
Gene Name
 Tcf20 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
474GLEGVPEKRLTDPGLacetylation[1, 2]
631GNTKVNEKTVGVIVSacetylation[2]
739GSLRYSYKESFGSAVacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1987 AA 
Protein Sequence
MQSFREQSSY HGNQQSYPQE VHSSSRIEEF SPRQAQMFQN FGGAGGGSSG TGSSSSGRRG 60
TAAAAAAMAS ETSGHQGYQG FRKEAGDFYY MAGNKDTVAA GTPQPPQRRP SGPVQSYGPP 120
QGSSFGNQYA SEGHVSQFQA QHSALGGVSH YQQDYTGPFS PGSAQYQQQA SSQQQQQQQQ 180
QQQQQQQQQQ QQVQQLRQQL YQSHQPLPQT TGQPASGSSH LQPMQRPSTL PSSAGYQLRV 240
GQFGQHYQSS ASSSSSSSFP SPQRFSQSGQ SYDGSYSVNA GSQYEGHNVG SNAQAYGTQS 300
NYSYQPQSMK NFEQAKIPPG NQQGQQQQQQ QPQPQQQQPQ QQQQQQQQQQ HPPQHVMQYT 360
NAATKMPLQS QVGQYNQPEV PVRSPMQFHQ NFSPISNPSP AASVVQSPSC SSTPSPLMQS 420
GENLQCGQGN VPMSSRNRIL QLMPQLSPTP SMMPSPNSHA AGFKGFGLEG VPEKRLTDPG 480
LSSLSALSSQ VANLPNTVQH MLLSDALTPQ KKTSKRPSSS SKKADSCTNS EGSSQPEEQL 540
KSPMAESLDG GCSSSSEDQG ERVRQLSGQS TSSDTTYKCG ASEKAGSSPT QGAQNEAPRL 600
STSPATRDEA ASPGAKDTSL SSEGNTKVNE KTVGVIVSRE AMTGRVEKSG GQDKGSQEDD 660
PAASQRPPSN SGVKEISHTS LPQPDPPGGG SKGNKNGDNN SSNHNGEGNG PSSHSAVGPS 720
FTGRTEPSKS PGSLRYSYKE SFGSAVPRNV SGYPQYPSGQ EKGDFGSHGE RKGRNEKFPS 780
LLQEVLQGYH HHPDRRYPRS AQEHQGMASG LEGTARPNIL VSQTNELASR GLLNKSIGSL 840
LENPHWGPWE RKSSSTAPEM KQINLSDYPI PRKFEIEPPS SAHEPGGSLS ERRSVICDIS 900
PLRQIVRDPG AHSLGHMGTD ARIGRNERLN PSLSQSVILP GGLVSMETKL KSQSGQIKEE 960
DFEQSKSQAS FNKKSGDHCH PTSIKHETYR GNASPGAAAH DSISDYGPQD SRSTPMRRVP 1020
GRVGSRETMR GRSSSQYHDF AEKLKMSPGR SRGPGGDPHH MNPHMTFSER ANRSSLHAPF 1080
SPNSESLASA YHTNTRAHAY GDPNTGLNSQ LHYKRQMYQQ QQEEYKDWAS SSAQGVIAAA 1140
QHRQEGPRKS PRQQQFLDRV RSPLKNDKDG MMYGPPVGTY HDPSTQEAGR CLMSSDGLPA 1200
KSMELKHSSQ KLQESCWDLS RQTSPAKSSG PPGMSNQKRY GPPHEPDGHG LAESAQSSKP 1260
SNVMLRLPGQ EDHSSQNPLI MRRRVRSFIS PIPSKRQSQD VKNSNADDKG RLLHPSKEGA 1320
DKAYNSYSHL SHSQDIKSIP KRDSSKDLPN PDNRNCPAVT LTSPAKTKIL PPRKGRGLKL 1380
EAIVQKITSP NIRRSASANS AEAGGDTVTL DDILSLKSGP PEGGTVATQE AEMEKRKCEV 1440
VSDLVSVTNQ ESNVEKPLPG PSEEWRGSGD DKVKTEAHVE TASTGKEPSG TMTSTASQKP 1500
GGNQGRPDGS LGGAAPLIFP DSKNVAPVGI LAPEANPKAE EKENDTVMIS PKQESFPPKG 1560
YFPSGKKKGR PIGSVNKQKK QQQQPPPPPQ PPQMPEGSAD GEPKPKKQRQ RRERRKPGAQ 1620
PRKRKTKQAV PIVEPQEPEI KLKYATQPLD KTDAKNKSFF PYIHVVNKCE LGAVCTIINA 1680
EEEEQTKLVR SRKGQRSLTP PPSSTESKVL PASSFMLQGP VVTESSVMGH LVCCLCGKWA 1740
SYRNMGDLFG PFYPQDYAAT LPKNPPPKRS SEMQSKVKVR HKSASNGSKT DTEEEEEQQQ 1800
QKEQRSLAAH PRFKRRHRSE DCGGGPRSLS RGLPCKKAAT EGSSEKTVSD TKPSVPTTSE 1860
GGPELELQIP ELPLDSNEFW VHEGCILWAN GIYLVCGRLY GLQEALEIAR EMKCSHCQEA 1920
GATLGCYNKG CSFRYHYPCA IDADCLLHEE NFSVRCPKHK PPLPCPLPPL QNKTAKGSLS 1980
TEQSERG 1987 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
 GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI. 
Interpro
 IPR001965; Znf_PHD. 
Pfam
  
SMART
 SM00249; PHD 
PROSITE
  
PRINTS