CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023459
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nuclear pore complex protein Nup214 
Protein Synonyms/Alias
 214 kDa nucleoporin; DNup214; Nucleoporin Nup214 
Gene Name
 Nup214 
Gene Synonyms/Alias
 CG3820 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
208GGTVKQFKPDLTLAKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex (By similarity). 
Sequence Annotation
 REPEAT 472 473 1.
 REPEAT 486 487 2.
 REPEAT 497 498 3.
 REPEAT 511 512 4.
 REPEAT 514 515 5.
 REPEAT 535 536 6.
 REPEAT 588 589 7.
 REPEAT 598 599 8.
 REPEAT 1009 1010 9.
 REPEAT 1075 1076 10.
 REPEAT 1077 1078 11.
 REPEAT 1097 1098 12.
 REPEAT 1106 1107 13.
 REPEAT 1135 1136 14.
 REPEAT 1218 1219 15.
 REPEAT 1229 1230 16.
 REPEAT 1240 1241 17.
 REPEAT 1356 1357 18.
 REPEAT 1388 1389 19.
 REPEAT 1399 1400 20.
 REPEAT 1434 1435 21.
 REPEAT 1449 1450 22.
 REPEAT 1458 1459 23.
 REPEAT 1472 1473 24.
 REPEAT 1481 1482 25.
 REPEAT 1487 1488 26.
 REPEAT 1507 1508 27.
 REPEAT 1512 1513 28.
 REPEAT 1539 1540 29.
 REPEAT 1547 1548 30.
 REPEAT 1562 1563 31.
 REPEAT 1571 1572 32.
 REPEAT 1584 1585 33.
 REPEAT 1588 1589 34.
 REPEAT 1601 1602 35.
 REPEAT 1617 1618 36.
 REPEAT 1623 1624 37.
 REPEAT 1629 1630 38.
 REPEAT 1635 1636 39.
 REPEAT 1641 1642 40.
 REPEAT 1647 1648 41.
 REPEAT 1650 1651 42.
 REPEAT 1662 1663 43.
 REPEAT 1686 1687 44.
 REPEAT 1702 1703 45.
 REGION 472 1703 45 X 2 AA repeats of F-G.
 REGION 650 672 Leucine-zipper 1.
 REGION 767 788 Leucine-zipper 2.  
Keyword
 Complete proteome; mRNA transport; Nuclear pore complex; Nucleus; Protein transport; Reference proteome; Repeat; Translocation; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1711 AA 
Protein Sequence
MAQNAPDCED TQDFQFKLHH KIVAFKKCGE PRSNVNLLAV SSSRGLLFAG SPTQPELKVI 60
IVKDLVNAKS TAQQPQARLV PLPSIPNYIA CSSDGNLLAV NHTQNGTSLL SIYAVLSFMT 120
PDVRPVYNIR LAAEDHVHGV QLLWNPVLPN SLAVVLSNGA LAMYALKEGG NFEMHSLDKN 180
QQVKCGCWSP KGKQIVLGFP GGTVKQFKPD LTLAKTLLCP PNIHDAPFDT IAIQWLSTFQ 240
FAVIFLQHGE DCSPSLYILN APKAGAPSYI NYYDICYSMN GPRNHQFVFS HVPQWNLLLV 300
VSANGVEVGI MRSTEAGDTP AWQQLTLLDE ARIEMPLSED KDETFPLGFA FDTSTTHQLT 360
INEKKLQTMP MVHVLSSDGE LLSFNFLNVL PTAVSVCSPP PPVADTSGQF KPLNMLLASE 420
EEEQPAWAAS PSKAPAATPA ASSDISFAFT PNTVTSTPAP SKDKQPSLFS GFGAAAAKAP 480
APQLSFGTAP TSSPVSFGAP TTNAAKPTTP FGGFGTQATT TAMGSMFSAS GANAFGGMAL 540
NKPAIASVTP RTAAPGSTVP ATPASAPANK PLYTVPLTFT PVDTKPATSA PPQIADESLK 600
PDDTEPIIKD MIALQIEAFS KDIQKQKEQT KELLKGIAAP SALRAYAKRL DDLQELNEQA 660
KDVEFELDVQ GLRQGLNEAY AIVAECRGKL EIYRKPEITR LMNSSSCDPS GRRMLARLQS 720
YVAANEAQLR LAQQHVDLQW EQFQDVVRRN SKSRMHMPCL EGIYQRLTRL QNLTSNQRIV 780
QNNIKSKLKE RGLLQAALLD QEKSRTRTNE AVDTLTDSIL TMSLSQVVDS NAAKLTRERL 840
QKIRNIVQLQ KINVICPQRP DRVGLKSEVI LETKRRAEQI KRAAAKPATA NKYTQAAVAP 900
PSPPDVAPTP AVAPMPQATV TVAPPLPKPM PSIPSVVEKP GVPTHPTTPV ATPFSFSQSI 960
PFVKTSTVTP TTNTVTPGEA AKPGLSIFGG STISSFSFGG GAAKSALSFG TGSPAVAAPT 1020
PKPNPLSAVE KPTPEPTKPK EQKAAESKEF KAVQPETEES KVPQKPKAET ENKSFGFGGF 1080
TGTGGTVGNT SSSPFSFGGL GSSLGFGGTA AAVPKSEPSS TATTSVATSA STAPFGIFSA 1140
ALAKPSNSEP ITTVTSNTTT ITSKPTNVIA SSSVTDAPSV TTTNAVTSST DPIGGLFSSV 1200
TICKPNTPAD TTKPANIFGG GLSAGSFSFG GTIDASKGLF GSTKPVATAP TSVTEANNKT 1260
DPISTTPSAI STTTATTTVS SPAVVPAAVT AAVPATSSTT VTSSTAVPGS AFSFSNAFST 1320
LSAGGAAAPT TSASAPLAAK SPTATSTGNN SSNSVFGGGF AVATSTAAPV ASPFQSAAKS 1380
PVSSANIFGS IPKAETSVFG GATTAPSNTT AAATPDAPPA GLFASAAISN PSPFGSPTTR 1440
APASGGNIFG QAVKPSVFGQ PAQAGDSGGS IFGGGSASTP FGSSSIFGGG NTQGAVGAPA 1500
AGSTSIFGQK VFGQSSAAAP AAGGNIFSNP VGSPQASPFG GGGNSIFGSP ATAPPASGGS 1560
IFGGGSSSGG FGSFTQTTPA QGGFGGGFGQ GGGGSVAQTG FGSPQAPQQQ TTTPGGFGAK 1620
PVFGGSPAFG ASPTFGGGAT FGSPKGFGGF GGASPVASPP PFGAAAKPAQ GNIFETLGGQ 1680
ESGLSFGNLA QTGNSNAQKP AFGGSSFMNY R 1711 
Gene Ontology
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005643; C:nuclear pore; IMP:UniProtKB.
 GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
 GO:0000059; P:protein import into nucleus, docking; IDA:UniProtKB.
 GO:0007184; P:SMAD protein import into nucleus; IMP:FlyBase. 
Interpro
 IPR026054; Nucleoporin.
 IPR015943; WD40/YVTN_repeat-like_dom. 
Pfam
  
SMART
  
PROSITE
  
PRINTS