CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011437
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein BFR2 
Protein Synonyms/Alias
 Brefeldin A resistance protein 2 
Gene Name
 BFR2 
Gene Synonyms/Alias
 YDR299W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
71KSKLRAEKGLELNDPacetylation[1]
79GLELNDPKYTGVKGSacetylation[1]
152QKRHALSKLIQQETKacetylation[1]
233RLLKENEKLFNNLFNacetylation[1]
296YRTAVLNKWSTKVSSacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Involved in endoplasmic reticulum to Golgi transport. Involved in a protein-transport step blocked by brefeldin A, which disrupts the Golgi apparatus and its incoming protein flux. May also be involved for mass growth or cell proliferation. 
Sequence Annotation
 MOD_RES 41 41 Phosphoserine.
 MOD_RES 44 44 Phosphoserine.
 MOD_RES 366 366 Phosphoserine.
 MOD_RES 372 372 Phosphoserine.
 MOD_RES 379 379 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; ER-Golgi transport; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 534 AA 
Protein Sequence
MEKSLADQIS DIAIKPVNKD FDIEDEENAS LFQHNEKNGE SDLSDYGNSN TEETKKAHYL 60
EVEKSKLRAE KGLELNDPKY TGVKGSRQAL YEEVSENEDE EEEEEEEEEK EEDALSFRTD 120
SEDEEVEIDE EESDADGGET EEAQQKRHAL SKLIQQETKQ AINKLSQSVQ RDASKGYSIL 180
QQTKLFDNII DLRIKLQKAV IAANKLPLTT ESWEEAKMDD SEETKRLLKE NEKLFNNLFN 240
RLINFRIKFQ LGDHITQNEE VAKHKLSKKR SLKELYQETN SLDSELKEYR TAVLNKWSTK 300
VSSASGNAAL SSNKFKAINL PADVQVENQL SDMSRLMKRT KLNRRNITPL YFQKDCANGR 360
LPELISPVVK DSVDDNENSD DGLDIPKNYD PRRKDNNAID ITENPYVFDD EDFYRVLLND 420
LIDKKISNAH NSESAAITIT STNARSNNKL KKNIDTKASK GRKLNYSVQD PIANYEAPIT 480
SGYKWSDDQI DEFFAGLLGQ RVNFNENEDE EQHARIENDE ELEAVKNDDI QIFG 534 
Gene Ontology
 GO:0030686; C:90S preribosome; IDA:SGD.
 GO:0005730; C:nucleolus; IDA:SGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0006364; P:rRNA processing; IMP:SGD.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 
Interpro
 IPR025160; AATF.
 IPR012617; AATF_C. 
Pfam
 PF13339; AATF-Che1
 PF08164; TRAUB 
SMART
  
PROSITE
  
PRINTS