| Tag | Content |
|---|
| CPLM ID | CPLM-015460 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | BTB/POZ domain-containing protein KCTD12 |
Protein Synonyms/Alias | Pfetin; Predominantly fetal expressed T1 domain |
Gene Name | Kctd12 |
Gene Synonyms/Alias | Pfet1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 231 | RDAQADAKFRRVARI | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization. |
Sequence Annotation | MOD_RES 119 119 Phosphotyrosine.
MOD_RES 187 187 Phosphoserine.
MOD_RES 189 189 Phosphoserine.
MOD_RES 198 198 Phosphothreonine. |
Keyword | Cell junction; Cell membrane; Complete proteome; Membrane; Phosphoprotein; Postsynaptic cell membrane; Reference proteome; Synapse. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 327 AA |
Protein Sequence | MALADSARGL PNGGGGGGGS GSSSSSAEPP LFPDIVELNV GGQVYVTRRC TVVSVPDSLL 60
WRMFTQQQPQ ELARDSKGRF FLDRDGFFFR YILDYLRDLQ LVLPDYFPER SRLQREAEYF 120
ELPELVRRLG APQQPGPGPP PPHSRRGVHK EGSLGDELLP LGYAEPEPQE GASAGAPSPT 180
LELASRSPSG GAAGPLLTPS QSLDGSRRSG YITIGYRGSY TIGRDAQADA KFRRVARITV 240
CGKTSLAKEV FGDTLNESRD PDRPPERYTS RYYLKFNFLE QAFDKLSESG FHMVACSSTG 300
TCAFASSTDQ SEDKIWTSYT EYVFCRE 327 |
Gene Ontology | GO:0030054; C:cell junction; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. GO:0045211; C:postsynaptic membrane; IDA:MGI. GO:0042734; C:presynaptic membrane; IDA:MGI. GO:0043235; C:receptor complex; IDA:MGI. GO:0051260; P:protein homooligomerization; IEA:InterPro. GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IGI:MGI. |
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PRINTS | |