UniProt Accession

 RER2_YEAST; P35196; D6VQ03 

Genbank Protein ID

 AB013497; Z26494; Z35871; BK006936 

Genbank Nucleotide ID

 BAA36577.1; CAA81271.1; CAA84938.1; DAA07123.1 

Protein Name

 Dehydrodolichyl diphosphate synthase RER2 

Protein Synonyms/Alias

 DEDOL-PP synthase; Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) 

Gene Name

 RER2 

Gene Synonyms/Alias

 YBR002C; YBR0107 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
135	GDLSLLDKSLLEDVR	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Cis-prenyl transferase involved in the dolichol synthesis, a family of long-chain polyprenols and which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP). 

Sequence Annotation

  

Keyword

 Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 286 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IDA:SGD.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0045547; F:dehydrodolichyl diphosphate synthase activity; IDA:SGD.
 GO:0019408; P:dolichol biosynthetic process; IDA:SGD.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.
 GO:0006486; P:protein glycosylation; IMP:SGD. 

Interpro

 IPR001441; UPP_synth-like.
 IPR018520; UPP_synth-like_CS. 

Pfam

 PF01255; Prenyltransf 

SMART

  

PROSITE

 PS01066; UPP_SYNTHASE 

PRINTS