UniProt Accession

 Q569X9_MOUSE; Q569X9; E9QAE5 

Genbank Protein ID

 AC117790; BC092260; BC106142; AK149389 

Genbank Nucleotide ID

 AAH92260.1; AAI06143.1; BAE28848.1 

Protein Name

 Cytochrome P450, family 2, subfamily c, polypeptide 67 

Protein Synonyms/Alias

 Protein Cyp2c67 

Gene Name

 Cyp2c67 

Gene Synonyms/Alias

 Cyp2c40; Cyp2c68 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
105	GRFPFFDKVTKGKGI	ubiquitination	[1]
110	FDKVTKGKGIGFSHG	ubiquitination	[1]
121	FSHGNVWKATRVFTI	ubiquitination	[1]
144	GKRTIENKVQEEAQW	ubiquitination	[1]
154	EEAQWLMKELKKTNG	ubiquitination	[1]
190	FQNRFDYKDKDFLSL	acetylation	[2]
190	FQNRFDYKDKDFLSL	ubiquitination	[1]
192	NRFDYKDKDFLSLIG	ubiquitination	[1]
235	GRHNKFFKNHTWIKS	ubiquitination	[1]
241	FKNHTWIKSYLLEKI	ubiquitination	[1]
247	IKSYLLEKIKEHEES	ubiquitination	[1]
249	SYLLEKIKEHEESLD	ubiquitination	[1]
322	KHTHITAKVQEEIDN	ubiquitination	[1]
375	HEVTCDTKFRNYFIP	ubiquitination	[1]
421	DDNGNFKKSDYFVPF	ubiquitination	[1]
432	FVPFSAGKRICVGES	ubiquitination	[1]
459	ILQNFKLKPLVDPKD	ubiquitination	[1]
465	LKPLVDPKDIDMTPK	ubiquitination	[1]
472	KDIDMTPKHSGFSKI	ubiquitination	[1]
478	PKHSGFSKIPPNFQM	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 491 AA 

Protein Sequence

Gene Ontology

 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. 

Interpro

 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I. 

Pfam

 PF00067; p450 

SMART

  

PROSITE

 PS00086; CYTOCHROME_P450 

PRINTS

 PR00463; EP450I.
 PR00385; P450.