UniProt Accession

 CD1B_HUMAN; P29016; Q5TDK9; Q5TDL0; Q9UMM2 

Genbank Protein ID

 M22173; M22168; M22169; M22170; M22171; M22172; M28826; AL121986; AL121986; BC069481; BC074747; BC104216; BC104217; M14665 

Genbank Nucleotide ID

 AAA51940.1; AAA51940.1; AAA51940.1; AAA51940.1; AAA51940.1; AAA51940.1; AAA51939.1; CAI10852.1; CAI10853.1; AAH69481.1; AAH74747.1; AAI04217.1; AAI04218.1; AAA51936.1 

Protein Name

 T-cell surface glycoprotein CD1b 

Protein Synonyms/Alias

 CD1b 

Gene Name

 CD1B 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
145	GLDFLSVKNASCVPS	ubiquitination	[1]
196	LGVLNAGKADLQRQV	ubiquitination	[1, 2]
204	ADLQRQVKPEAWLSS	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 

Functional Description

 Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. 

Sequence Annotation

 DOMAIN 185 295 Ig-like.
 MOTIF 329 332 Internalization signal.
 CARBOHYD 38 38 N-linked (GlcNAc...).
 CARBOHYD 75 75 N-linked (GlcNAc...).
 CARBOHYD 146 146 N-linked (GlcNAc...) (Potential).
 CARBOHYD 258 258 N-linked (GlcNAc...) (Potential).
 DISULFID 120 184
 DISULFID 149 163
 DISULFID 224 279  

Keyword

 3D-structure; Adaptive immunity; Alternative splicing; Cell membrane; Complete proteome; Disulfide bond; Endosome; Glycoprotein; Immunity; Immunoglobulin domain; Lysosome; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 333 AA 

Protein Sequence

Gene Ontology

 GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; TAS:ProtInc.
 GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; TAS:ProtInc.
 GO:0019882; P:antigen processing and presentation; IEA:InterPro.
 GO:0006955; P:immune response; IEA:InterPro. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003597; Ig_C1-set.
 IPR011161; MHC_I-like_Ag-recog.
 IPR011162; MHC_I/II-like_Ag-recog. 

Pfam

 PF07654; C1-set 

SMART

 SM00407; IGc1 

PROSITE

 PS50835; IG_LIKE 

PRINTS