CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035582
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Ahcyl1 
Protein Synonyms/Alias
 S-adenosylhomocysteine hydrolase-like 1 (Predicted) 
Gene Name
 Ahcyl1 
Gene Synonyms/Alias
 Ahcyl1_predicted; rCG_28904 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
193LTHWVYKKYPNVFKKacetylation[1]
199KKYPNVFKKIRGIVEacetylation[1]
312MDGFRVVKLNEVIRQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 BINDING 108 108 Substrate (By similarity).
 BINDING 182 182 Substrate (By similarity).
 BINDING 207 207 Substrate (By similarity).
 BINDING 237 237 Substrate (By similarity).
 BINDING 241 241 Substrate (By similarity).  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 475 AA 
Protein Sequence
MQEFTKFPTK TGRRSLSRSI SQSSTDSYSS AASYTDSSDD EVSPREKQQT NSKGSSNFCV 60
KNIKQAEFGR REIEIAEQDM SALISLRKRA QGEKPLAGAK IVGCTHITAQ TAVLIETLCA 120
LGAQCRWSAC NIYSTQNEVA AALAEAGVAV FAWKGESEDD FWWCIDRCVN MDGWQANMIL 180
DDGGDLTHWV YKKYPNVFKK IRGIVEESVT GVHRLYQLSK AGKLCVPAMN VNDSVTKQKF 240
DNLYCCRESI LDGLKRTTDV MFGGKQVVVC GYGEVGKGCC AALKALGAIV YITEIDPICA 300
LQACMDGFRV VKLNEVIRQV DVVITCTGNK NVVTREHLDR MKNSCIVCNM GHSNTEIDVT 360
SLRTPELTWE RVRSQVDHVI WPDGKRVVLL AEGRLLNLSC STVPTFVLSI TATTQALALI 420
ELYNAPEGRY KQDVYLLPKK MDTNGRITMT SPHEPRNSNR VFFKITFIFF LLLSF 475 
Gene Ontology
 GO:0004013; F:adenosylhomocysteinase activity; IEA:InterPro.
 GO:0006378; P:mRNA polyadenylation; IEA:Compara.
 GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
 GO:0010765; P:positive regulation of sodium ion transport; IEA:Compara.
 GO:0006611; P:protein export from nucleus; IEA:Compara.
 GO:0044070; P:regulation of anion transport; IEA:Compara.
 GO:0032412; P:regulation of ion transmembrane transporter activity; IEA:Compara.
 GO:0031440; P:regulation of mRNA 3'-end processing; IEA:Compara. 
Interpro
 IPR000043; Adenosylhomocysteinase.
 IPR015878; Ado_hCys_hydrolase_NAD-bd.
 IPR016040; NAD(P)-bd_dom.
 IPR020082; S-Ado-L-homoCys_hydrolase_CS. 
Pfam
 PF05221; AdoHcyase
 PF00670; AdoHcyase_NAD 
SMART
 SM00996; AdoHcyase
 SM00997; AdoHcyase_NAD 
PROSITE
 PS00738; ADOHCYASE_1
 PS00739; ADOHCYASE_2 
PRINTS