CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008288
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sulfate transporter 
Protein Synonyms/Alias
 Diastrophic dysplasia protein; Solute carrier family 26 member 2 
Gene Name
 SLC26A2 
Gene Synonyms/Alias
 DTD; DTDST 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
40RESSTDFKQFETNDQubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 Sulfate transporter. May play a role in endochondral bone formation. 
Sequence Annotation
 DOMAIN 568 719 STAS.
 MOD_RES 12 12 Phosphoserine.
 MOD_RES 16 16 Phosphoserine.
 CARBOHYD 199 199 N-linked (GlcNAc...) (Potential).
 CARBOHYD 205 205 N-linked (GlcNAc...) (Potential).
 CARBOHYD 357 357 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Disease mutation; Dwarfism; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 739 AA 
Protein Sequence
MSSESKEQHN VSPRDSAEGN DSYPSGIHLE LQRESSTDFK QFETNDQCRP YHRILIERQE 60
KSDTNFKEFV IKKLQKNCQC SPAKAKNMIL GFLPVLQWLP KYDLKKNILG DVMSGLIVGI 120
LLVPQSIAYS LLAGQEPVYG LYTSFFASII YFLLGTSRHI SVGIFGVLCL MIGETVDREL 180
QKAGYDNAHS APSLGMVSNG STLLNHTSDR ICDKSCYAIM VGSTVTFIAG VYQVAMGFFQ 240
VGFVSVYLSD ALLSGFVTGA SFTILTSQAK YLLGLNLPRT NGVGSLITTW IHVFRNIHKT 300
NLCDLITSLL CLLVLLPTKE LNEHFKSKLK APIPIELVVV VAATLASHFG KLHENYNSSI 360
AGHIPTGFMP PKVPEWNLIP SVAVDAIAIS IIGFAITVSL SEMFAKKHGY TVKANQEMYA 420
IGFCNIIPSF FHCFTTSAAL AKTLVKESTG CHTQLSGVVT ALVLLLVLLV IAPLFYSLQK 480
SVLGVITIVN LRGALRKFRD LPKMWSISRM DTVIWFVTML SSALLSTEIG LLVGVCFSIF 540
CVILRTQKPK SSLLGLVEES EVFESVSAYK NLQIKPGIKI FRFVAPLYYI NKECFKSALY 600
KQTVNPILIK VAWKKAAKRK IKEKVVTLGG IQDEMSVQLS HDPLELHTIV IDCSAIQFLD 660
TAGIHTLKEV RRDYEAIGIQ VLLAQCNPTV RDSLTNGEYC KKEEENLLFY SVYEAMAFAE 720
VSKNQKGVCV PNGLSLSSD 739 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
 GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
 GO:0015116; F:sulfate transmembrane transporter activity; TAS:ProtInc.
 GO:0001503; P:ossification; IEA:Compara.
 GO:0008272; P:sulfate transport; TAS:ProtInc. 
Interpro
 IPR018045; S04_transporter_CS.
 IPR002645; STAS_dom.
 IPR001902; SulP_transpt.
 IPR011547; Sulph_transpt. 
Pfam
 PF01740; STAS
 PF00916; Sulfate_transp 
SMART
  
PROSITE
 PS01130; SLC26A
 PS50801; STAS 
PRINTS