UniProt Accession

 B2R6U8_HUMAN; B2R6U8 

Genbank Protein ID

 AK312721 

Genbank Nucleotide ID

 BAG35595.1 

Protein Name

 cDNA, FLJ93125, highly similar to Homo sapiens cleavage and polyadenylation specific factor 5, 25 kDa(CPSF5), mRNA 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
23	GVTQFGNKYIQQTKP	ubiquitination	[1]
29	NKYIQQTKPLTLERT	ubiquitination	[1]
182	FLVQLQEKALFAVPK	ubiquitination	[1]
192	FAVPKNYKLVAAPLF	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

  

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 227 AA 

Protein Sequence

Gene Ontology

 GO:0005849; C:mRNA cleavage factor complex; IEA:InterPro.
 GO:0016787; F:hydrolase activity; IEA:InterPro.
 GO:0003729; F:mRNA binding; IEA:InterPro.
 GO:0006378; P:mRNA polyadenylation; IEA:InterPro. 

Interpro

 IPR016706; Cleav_polyA_spec_factor_su5.
 IPR000086; NUDIX_hydrolase_dom.
 IPR015797; NUDIX_hydrolase_dom-like. 

Pfam

 PF13869; NUDIX_2 

SMART

  

PROSITE

 PS51462; NUDIX 

PRINTS