| Tag | Content |
|---|
| CPLM ID | CPLM-001799 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pancreatic alpha-amylase |
Protein Synonyms/Alias | PA; 1,4-alpha-D-glucan glucanohydrolase |
Gene Name | Amy2 |
Gene Synonyms/Alias | Amy2a |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 190 | EKDYVRTKVADYMNH | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | ACT_SITE 209 209 Nucleophile (By similarity).
ACT_SITE 245 245 Proton donor (By similarity).
METAL 115 115 Calcium (By similarity).
METAL 170 170 Calcium; via carbonyl oxygen (By
METAL 179 179 Calcium (By similarity).
METAL 213 213 Calcium; via carbonyl oxygen (By
BINDING 207 207 Chloride (By similarity).
BINDING 310 310 Chloride (By similarity).
BINDING 349 349 Chloride (By similarity).
MOD_RES 16 16 Pyrrolidone carboxylic acid.
DISULFID 43 101 By similarity.
DISULFID 85 130 By similarity.
DISULFID 156 172 By similarity.
DISULFID 390 396 By similarity.
DISULFID 462 474 By similarity. |
Keyword | Calcium; Carbohydrate metabolism; Chloride; Complete proteome; Direct protein sequencing; Disulfide bond; Glycosidase; Hydrolase; Metal-binding; Polymorphism; Pyrrolidone carboxylic acid; Reference proteome; Secreted; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 508 AA |
Protein Sequence | MKFVLLLSLI GFCWAQYDPH TSDGRTAIVH LFEWRWVDIA KECERYLAPK GFGGVQVSPP 60
NENVVVHNPS RPWWERYQPI SYKICTRSGN EDEFRDMVTR CNNVGVRIYV DAVINHMCGA 120
GNPAGTSSTC GSYLNPNNRE FPAVPYSAWD FNDNKCNGEI DNYNDAYQVR NCRLTGLLDL 180
ALEKDYVRTK VADYMNHLID IGVAGFRLDA AKHMWPGDIK AVLDKLHNLN TKWFSQGSRP 240
FIFQEVIDLG GEAIKGSEYF GNGRVTEFKY GAKLGTVIRK WNGEKMSYLK NWGEGWGLVP 300
SDRALVFVDN HDNQRGHGAG GSSILTFWDA RMYKMAVGFM LAHPYGFTRV MSSYRWNRNF 360
QNGKDQNDWI GPPNNNGVTK EVTINADTTC GNDWVCEHRW RQIRNMVAFR NVVNGQPFSN 420
WWDNNSNQVA FSRGNRGFIV FNNDDWALSA TLQTGLPAGT YCDVISGDKV DGNCTGLRVN 480
VGSDGKAHFS ISNSAEDPFI AIHADSKL 508 |
Gene Ontology | GO:0005615; C:extracellular space; ISS:UniProtKB. GO:0004556; F:alpha-amylase activity; ISS:UniProtKB. GO:0005509; F:calcium ion binding; ISS:UniProtKB. GO:0031404; F:chloride ion binding; ISS:UniProtKB. GO:0016052; P:carbohydrate catabolic process; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |