CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025543
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine/threonine-protein kinase TAO3 
Protein Synonyms/Alias
  
Gene Name
 Taok3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
370QHERELQKLEQRVSLacetylation[1, 2]
395EELAALQKERSERIKubiquitination[3]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 438 AA 
Protein Sequence
MSGYKRMRRQ HQKQLIALEN KLKAEMDEHR LKLQKEVETH ANNSSIELEK LAKKQVATIE 60
KEAKVAAADE KKFQQQILAQ QKKDLTTFLE SQKKQYKICK EKIKEEMNED HSTPKKEKQE 120
RISKHKENLQ HTQAEEEAHL LTQQRLYYDR NCRFFKRKIM IKRHEVEQQN IREELNKKRT 180
QKEMEHAMLI RHDESTRELE YRQLHTLQKL RMDLIRLQHQ TELENQLEYN KRRERELHRK 240
HVMELRQQPK NLKAMEMQIK KQFQDTCKVQ TKQYKALKNH QLEVTPKNEH KAILKTLKDE 300
QTRKLAILAE QYEQSINEMM ASQALRLDEA QEAECQALRL QLQQEMELLN AYQSKIKMQT 360
EAQHERELQK LEQRVSLRRA HLEQKIEEEL AALQKERSER IKTLLERQER ETETFDMESL 420
RMGFGNLVTL DFPKEDYR 438 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:Compara.
 GO:0031572; P:G2 DNA damage checkpoint; IEA:Compara.
 GO:0000165; P:MAPK cascade; IEA:Compara.
 GO:0046329; P:negative regulation of JNK cascade; IEA:Compara.
 GO:0046330; P:positive regulation of JNK cascade; IEA:Compara.
 GO:0043507; P:positive regulation of JUN kinase activity; IEA:Compara.
 GO:0046777; P:protein autophosphorylation; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS