CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012898
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leucine-rich repeat neuronal protein 1 
Protein Synonyms/Alias
 Neuronal leucine-rich repeat protein 1; NLRR-1 
Gene Name
 Lrrn1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
703KDGSADTKPTQVDTSubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
 DOMAIN 26 72 LRRNT.
 REPEAT 73 95 LRR 1.
 REPEAT 96 117 LRR 2.
 REPEAT 120 141 LRR 3.
 REPEAT 144 165 LRR 4.
 REPEAT 168 189 LRR 5.
 REPEAT 192 213 LRR 6.
 REPEAT 216 237 LRR 7.
 REPEAT 240 261 LRR 8.
 REPEAT 264 285 LRR 9.
 DOMAIN 371 424 LRRCT.
 DOMAIN 424 515 Ig-like C2-type.
 DOMAIN 522 614 Fibronectin type-III.
 CARBOHYD 69 69 N-linked (GlcNAc...) (Potential).
 CARBOHYD 96 96 N-linked (GlcNAc...) (Potential).
 CARBOHYD 106 106 N-linked (GlcNAc...) (Potential).
 CARBOHYD 117 117 N-linked (GlcNAc...) (Potential).
 CARBOHYD 385 385 N-linked (GlcNAc...) (Potential).
 CARBOHYD 517 517 N-linked (GlcNAc...) (Potential).
 CARBOHYD 582 582 N-linked (GlcNAc...) (Potential).
 CARBOHYD 611 611 N-linked (GlcNAc...) (Potential).
 DISULFID 447 499 By similarity.  
Keyword
 Complete proteome; Disulfide bond; Glycoprotein; Immunoglobulin domain; Leucine-rich repeat; Membrane; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 716 AA 
Protein Sequence
MARLSPGKAA CWMVLGLLIP SLTESSILNS ECPQLCVCEI RPWFTPQSTY REATTVDCND 60
LRLTRIPGNL SSDTQVLLLQ SNNIAKTVDE LQQLFNLTEL DFSQNNFTNI KEVGLANLTQ 120
LTTLHLEENQ ISEMTDYCLQ DLSNLQELYI NHNQISSISA NAFSGLKNLL RLHLNSNKLK 180
VIDSRWFDST PNLEILMIGE NPVIGILDMN FRPLSNLRSL VLAGMYLTDI PGNALVGLDS 240
LESLSFYDNK LIKVPQLALQ KVPNLKFLDL NKNPIHKIQE GDFKNMLRLK ELGINNMGEL 300
VSVDRYALDN LPELTKLEAT NNPKLSYIHR LAFRSVPALE SLMLNNNALN AVYQKTVESL 360
PNLREISIHS NPLRCDCVIH WINSNKTNIR FMEPLSMFCA MPPEYRGQQV KEVLIQDSSE 420
QCLPMISHDT FPNHLNMDIG TTLFLDCRAM AEPEPEIYWV TPIGNKITVE TLSDKYKLSS 480
EGTLEIANIQ IEDSGRYTCV AQNVQGADTR VATIKVNGTL LDGAQVLKIY VKQTESHSIL 540
VSWKVNSNVM TSNLKWSSAT MKIDNPHITY TARVPVDVHE YNLTHLQPST DYEVCLTVSN 600
IHQQTQKSCV NVTTKTAAFA LDISDHETST ALAAVMGSMF AVISLASIAI YIAKRFKRKN 660
YHHSLKKYMQ KTSSIPLNEL YPPLINLWEG DSDKDKDGSA DTKPTQVDTS RSYYMW 716 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR000483; Cys-rich_flank_reg_C.
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003598; Ig_sub2.
 IPR001611; Leu-rich_rpt.
 IPR003591; Leu-rich_rpt_typical-subtyp.
 IPR000372; LRR-contain_N. 
Pfam
 PF07679; I-set
 PF00560; LRR_1 
SMART
 SM00060; FN3
 SM00408; IGc2
 SM00369; LRR_TYP
 SM00082; LRRCT
 SM00013; LRRNT 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE
 PS51450; LRR 
PRINTS