CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035607
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dysferlin (Predicted), isoform CRA_a 
Protein Synonyms/Alias
 Protein Dysf 
Gene Name
 Dysf 
Gene Synonyms/Alias
 Dysf_predicted; rCG_56240 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
151PPHYPGGKRKRSSAPacetylation[1]
1558YIKISIGKKSVSDQDacetylation[1]
1607DLLSKDEKIGETVIDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2029 AA 
Protein Sequence
MLCCLLARAS NLPNVKKDRR SDPVASLIFR EAKIPLQEVL ATPSLSASFN APLLDSKQQP 60
TGASLVLQVS YTPPPGAAPL FPPPASLAPS PTLPDMDLVA DTGGEEDTED QGLTGDEAEL 120
FPDPSVAVGP GGPTTPKKPP SHPPPHYPGG KRKRSSAPPR KLLSDKPQDF QIRVQVIEGR 180
QLPGVNIKPV VKVTAAGQTK RTRIQKGNSP LFNETLFFNV FDSPLELFDE PIFITVVDSR 240
SLRTDALLGE FRMDVGTVYR EPRHAYLRKW LLLSDPDDFS AGARGYLKAS LCVLGPGDEA 300
PLDKKDPSED KEDIEGNLLR PTGVALRGAH FCLKLFRAED LPQMDDAVMD NVKQIFGFDS 360
NKKNLVDPFV EVSFAGKMLC SKILEKTANP QWNQNITLPA MFPSMCEKMR IRVMDWDRLT 420
HNDTVATTYL GMSKISATGG EIEEEPAGVL KSPATDLDDN LGFLPTFGPC YVNLYGSPRE 480
FTGFPDPYAE LNTGKGEGVA YRGRLLLSLE TKLVEHSEQK VEDLPADDIL RVEKYLRRRK 540
YSLFAAFYSA TMLQDVDDAI QFEVSIGNYG NKFDTTCLPL ASTTQYSRAV FDGCHYYYLP 600
WGNVKPVVVL SSYWEDISHR VETQNQLLRI ADRLEANLEQ VHLALKAQCS SEDVDALVAQ 660
LTDELLADCS QPLCDIHEIP SATHLDQYLF RLRSRHLSQI KEAALALKLG HSELSTALEQ 720
AEDWLLHLRA LAEEPQNSLP DIIIWMLQGD KRVAYQRVPA HEVLFSRRGP SYCGRNCGNL 780
QTIFLKYPME GMPGPRMPVQ IRIKLWFGLS VDEKEFNQFA EGKLSVFAET YENQTKLALV 840
GNWGTTGLTY PKFSDVTGKI KLPKDSFRPS AGWAWAGDWF VCPEKTLLHD ADAGHLSFVE 900
EVFENQTRLP GGQWIYMSDN YTDVNGEKVL PKDDIECPLG WKWEDEEWST DLNRAVDEQG 960
WEYSITIPPD RKPKHWVPVE KMYYTHRRRR WVRLRRRDLS QMEALKKHRQ AEAEGEGWEY 1020
ASLFGWKFHL EYRKTDAFRR RRWRRRMEPL EKTGPAAVFA LEGALGGMVD DKSEDSMSVS 1080
TLSFGVNRPT ISCIFDYGNR YHLRCYLYQA RDLPAMDKDS FSDPYAIVSF LHQSQKTVVE 1140
KNTLNPTWDQ TLIFYEIEIF GEPASVAERP PSIVVELYDH DTYGADEFMG RCICQPSLER 1200
MPRLAWFPLT RGSQPAGELL AAFELIQREK PAIHHIPGFE MHETSRILDE TEDTDLPYPP 1260
PQREANIYMV PQNIKPALQR TAIEILAWGL RNIKSYQMAS VSSPSLVVEC GGQTVQSCVI 1320
RNLRKNPNFD VCTLFMEVML PREDLYCPPI VVKVIDNRQF GRRPVVGQCT IRSLENFLCD 1380
PYSAESPSPQ GGPDDVSLLS PGEDVLIDID DKEPLIPVQE EEFIDWWSKF FASIGEREKC 1440
GSYLEKDFDT LKVYDTQLEN VEAFGGLSDF CNTFKLYRGK TQEDTEDPSV IGEFKGLFKI 1500
YPLPEDPAIP MPPRQFHQLA AQGPQECLVR IYIIRAFGLQ PKDPNGKCDP YIKISIGKKS 1560
VSDQDNYIPC TLEPVFGKMF ELTCTLPLEK DLKITLYDYD LLSKDEKIGE TVIDLENRLL 1620
SKFGARCGLP QTYCVSGPNQ WRDQLRPSQL LHLFCQQHRV KAPVYRTDRV TFQDKEYTIQ 1680
EIEAGRLPNP HLGPVEERLA LHVLQQQGLV PEHVESRPLY SPLQPDIEQG KLQMWIDIFP 1740
KVLGRPGPPF NITPRKARRF FLRCIIWNTK DVILDDLSLT GEKMSDIYVK GWMVGFEEHK 1800
QKTDVHYRSL GGEGNFNWRF VFPFDYLPAE QVCAVAKKDA FWRLDKTESK IPARVVFQIW 1860
DNDKFSFDDF LGSLQLDLNR MPKPAKTAEK CSLDQLDDTF HPEWFVSLFE QKTVKGWWPC 1920
VTEEGAKKIL AGKLEMTLEI VAESEHEERP AGQGRDEPNM NPKLEDPRRP DTSFLWFTSP 1980
YKTMKFILWR RFRCAIILFI ILFILLLFLG VFVYAFPNYA AMKLVKPFR 2029 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR012968; FerIin-domain.
 IPR012560; Ferlin_A-domain.
 IPR012561; Ferlin_B-domain.
 IPR010482; Peroxin/Dysferlin.
 IPR006614; Peroxin/Ferlin. 
Pfam
 PF00168; C2
 PF08165; FerA
 PF08150; FerB
 PF08151; FerI
 PF06398; Pex24p 
SMART
 SM00239; C2
 SM00694; DysFC
 SM00693; DysFN 
PROSITE
 PS50004; C2 
PRINTS