CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040254
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 CUGBP Elav-like family member 2 
Protein Synonyms/Alias
  
Gene Name
 Celf2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
447SAKVFIDKQTNLSKCacetylation[1, 2]
447SAKVFIDKQTNLSKCubiquitination[3]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 497 AA 
Protein Sequence
XNGTANKMNG ALDHSDQPDP DAIKMFVGQI PRSWSEKELK ELFEPYGAVY QINVLRDRSQ 60
NPPQSKGCCF VTFYTRKAAL EAQNALHNIK TLPGMHHPIQ MKPADSEKSN AVEDRKLFIG 120
MVSKKCNEND IRVMFSPFGQ IEECRILRGP DGLSRGCAFV TFSTRAMAQN AIKAMHQSQT 180
MEGCSSPIVV KFADTQKDKE QRRLQQQLAQ QMQQLNTATW GNLTGLGGLT PQYLALLQQA 240
TSSSNLGAFS GIQQMAGMNA LQLQNLATLA AAAAAAQTSA TSTNANPLSS TSSALGALTS 300
PVAASTPNST AGAAMNSLTS LGTLQGLAGA TVGLNNINAL AVAQMLSGMA ALNGGLGATG 360
LTNGTAGTMD ALTQAYSGIQ QYAAAALPTL YSQSLLQQQS AAGSQKEGPE GANLFIYHLP 420
QEFGDQDILQ MFMPFGNVIS AKVFIDKQTN LSKCFGFVSY DNPVSAQAAI QAMNGFQIGM 480
KRLKVQLKRS KNDSKPY 497 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0006376; P:mRNA splice site selection; IDA:MGI. 
Interpro
 IPR002343; Hud_Sxl_RNA.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS
 PR00961; HUDSXLRNA.