UniProt Accession

 F8VNZ6_HUMAN; F8VNZ6 

Genbank Protein ID

 AC073896 

Genbank Nucleotide ID

  

Protein Name

 E3 ubiquitin-protein ligase NRDP1 

Protein Synonyms/Alias

  

Gene Name

 RNF41 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
103	KRDIQLLKAYMRAIR	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 146 AA 

Protein Sequence

Gene Ontology

 GO:0031386; F:protein tag; IEA:InterPro.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0045619; P:regulation of lymphocyte differentiation; IEA:Compara.
 GO:0045637; P:regulation of myeloid cell differentiation; IEA:Compara. 

Interpro

 IPR013323; SIAH-type.
 IPR008974; TRAF-like.
 IPR015036; USP8_interacting.
 IPR013010; Znf_SIAH. 

Pfam

 PF08941; USP8_interact 

SMART

  

PROSITE

 PS51081; ZF_SIAH 

PRINTS