UniProt Accession

 Q9JIA6_MOUSE; Q9JIA6 

Genbank Protein ID

 AL607108; AF246459; BC016602; AK045694; AK168716; CH466558 

Genbank Nucleotide ID

 AAF78226.1; AAH16602.1; BAC32460.1; BAE40558.1; EDL34544.1 

Protein Name

 Galactokinase 

Protein Synonyms/Alias

 Galactokinase 1; Galactokinase 1, isoform CRA_c 

Gene Name

 Galk1 

Gene Synonyms/Alias

 mCG_6616 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
217	LVPLSDPKLAVLITN	ubiquitination	[1]
272	AGRELMSKEGFRRAR	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 392 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004335; F:galactokinase activity; IDA:MGI.
 GO:0005534; F:galactose binding; IEA:Compara.
 GO:0019402; P:galactitol metabolic process; IMP:MGI.
 GO:0006012; P:galactose metabolic process; IDA:MGI. 

Interpro

 IPR000705; Galactokinase.
 IPR019741; Galactokinase_CS.
 IPR019539; GalKase_gal-bd.
 IPR013750; GHMP_kinase_C_dom.
 IPR006204; GHMP_kinase_N_dom.
 IPR006203; GHMP_knse_ATP-bd_CS.
 IPR006206; Mevalonate/galactokinase.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr. 

Pfam

 PF10509; GalKase_gal_bdg
 PF08544; GHMP_kinases_C
 PF00288; GHMP_kinases_N 

SMART

  

PROSITE

 PS00106; GALACTOKINASE
 PS00627; GHMP_KINASES_ATP 

PRINTS

 PR00473; GALCTOKINASE.
 PR00959; MEVGALKINASE.