CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011581
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable transporter MCH4 
Protein Synonyms/Alias
  
Gene Name
 MCH4 
Gene Synonyms/Alias
 YOL119C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
11IPIIANSKRFLFSKDubiquitination[1]
53NAADAILKKNSDQVDubiquitination[1]
54AADAILKKNSDQVDLubiquitination[1, 2]
65QVDLDVNKLTNVTSRubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 Probable transporter. Does not act in the transport of monocarboxylic acids across the plasma membrane. 
Sequence Annotation
 CARBOHYD 131 131 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 501 AA 
Protein Sequence
MLNIPIIANS KRFLFSKDHE AQSTRDHDVE LETREGPSSG YNPNFNAADA ILKKNSDQVD 60
LDVNKLTNVT SRVLNTPEAS LIYDDDREFP DGGLKAWLVV FGAFMGLVPV FGLINSLGAI 120
ESYISKHQLA NISSSTISWI FSLYLAISFL SCILSGGYFD RNGSIGLMCT GTVIYAGGLF 180
ALANCKSVWQ FILAFSVCSG LGTGILMTPL IGTVATWFLK RRGIATSIST MGGSIGGIVF 240
PIMLRKLYKE VGFQWAIRIL SFICLTCLIC ASVLARERTK PVVQPFKSKA EVAKWYISSV 300
FNWRYFLEGK FLFVAIGASF AESSLTSCAT YLASYSMTRG NTENVAYTMI TASNAVGILG 360
RYIPGYFADK FIGRFNVEII TISMAALFNF VMWLPFGGNT KVLWAYVCLW GFSTGSILSL 420
TPVCIGQISK TTDFGKRYAT VYLLQALVTI PVLPIGGTLI GKGTVANYNH FIIFNSALMA 480
AGAACYIISR HICVGAKLCK F 501 
Gene Ontology
 GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
 GO:0005215; F:transporter activity; ISS:SGD. 
Interpro
 IPR011701; MFS.
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt. 
Pfam
 PF07690; MFS_1 
SMART
  
PROSITE
 PS50850; MFS 
PRINTS