CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043160
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 
Protein Synonyms/Alias
  
Gene Name
 HDDC3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
25KHRQQRRKDPEGTPYacetylation[1, 2]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 143 AA 
Protein Sequence
MGSEAAQLLE AADFAARKHR QQRRKDPEGT PYINHPIGVA RILTHEAGIT DIVVLQAALL 60
HDTVEDTDTT LDEVELHFGA QVRRLVEEVT DDKTLPKLER KRLQVEQAPH SSPGAKLVKL 120
ADKLYNLRDL NRCTPEGTLS YGL 143 
Gene Ontology
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC. 
Interpro
 IPR026020; (p)ppGpp_Synthase.
 IPR003607; HD/PDEase_dom. 
Pfam
  
SMART
 SM00471; HDc 
PROSITE
  
PRINTS