UniProt Accession

 ORN_RAT; Q5U1X1 

Genbank Protein ID

 BC086420 

Genbank Nucleotide ID

 AAH86420.1 

Protein Name

 Oligoribonuclease, mitochondrial 

Protein Synonyms/Alias

 RNA exonuclease 2 homolog; Small fragment nuclease 

Gene Name

 Rexo2 

Gene Synonyms/Alias

 Smfn 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
148	GNSVHADKKFLDKHM	acetylation	[1]
153	ADKKFLDKHMPQFMK	acetylation	[1]
160	KHMPQFMKHLHYRII	acetylation	[1]
173	IIDVSTVKELCRRWY	acetylation	[1]
205	DDISESIKELQFYRN	acetylation	[1]
234	IENGENEKPVS****	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily

Sequence Annotation

 DOMAIN 43 207 Exonuclease.
 MOD_RES 122 122 Phosphotyrosine (By similarity).
 MOD_RES 184 184 Phosphotyrosine (By similarity).  

Keyword

 Complete proteome; Exonuclease; Hydrolase; Manganese; Mitochondrion; Nuclease; Phosphoprotein; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 237 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0008408; F:3'-5' exonuclease activity; IEA:Compara.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 

Interpro

 IPR006055; Exonuclease.
 IPR013520; Exonuclease_RNaseT/DNA_pol3.
 IPR022894; Oligoribonuclease.
 IPR012337; RNaseH-like_dom. 

Pfam

 PF00929; RNase_T 

SMART

 SM00479; EXOIII 

PROSITE

  

PRINTS