CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013852
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dehydrogenase/reductase SDR family member 7B 
Protein Synonyms/Alias
  
Gene Name
 Dhrs7b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
87VLCGRNVKALEEFTRubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
 Putative oxidoreductase (Potential). 
Sequence Annotation
 NP_BIND 56 80 NAD or NADP (By similarity).
 ACT_SITE 207 207 Proton acceptor (By similarity).
 BINDING 194 194 Substrate (Potential).  
Keyword
 Alternative splicing; Complete proteome; Membrane; NAD; NADP; Oxidoreductase; Peroxisome; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 325 AA 
Protein Sequence
MISPSSRKGM LKERAMDLVT QTTILPLLFG CLGIFSLFRL LQRTRSKAYL RNAVVVVTGA 60
TSGLGKECAR VFHAAGAKVV LCGRNVKALE EFTRELADSS SSQGQTHQPC VVTFDLADPG 120
AIAPAAAEIL QCFGYVDILI NNAGISYRGA ISDTIVDVDR KVMEINYFGP VALTKALLPS 180
MVERKRGHIV AISSIQGKIS IPFRSAYAAS KHATQAFFDC LRAEMKDSDI EVTVISPGYI 240
HTNLSVNAVT ADGSRYGALD KNTAQGRSAV EVAQDIFDAV GKKKKDVLLT DFLPTMAVYI 300
RTLAPRLFFR IMASRARKER KSKNS 325 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. 
Interpro
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 
Pfam
 PF00106; adh_short 
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.
 PR00080; SDRFAMILY.