| Tag | Content |
|---|
| CPLM ID | CPLM-017787 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Monocarboxylate transporter 5 |
Protein Synonyms/Alias | MCT 5 |
Gene Name | Slc16a4 |
Gene Synonyms/Alias | Mct5 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 225 | TEPEASYKTETSKCK | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity). |
Sequence Annotation | |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 500 AA |
Protein Sequence | MVKKEKTPSP YTKPLDGGWG WMVVLHFFLV NVFVMGMTKT FAIFFVVFQE EFEGTSEQIG 60
WIGSIMSSLR FSAGPLAAII CDVLGEKATS ILGTFLVSGG YVISSWATGI PFLCVTMGLL 120
PGLGSAFLYQ VAAVVITKYF KKRLGLSTAI ARSGMGLTFL LAPFTKFLID LYDWTGALIL 180
FGAIILNLVP SSMLLRPIHS QSNNNSDIEN KGSILSATEP EASYKTETSK CKETQEPFIK 240
DSTMKKSEQP TTTLTVLGNQ SEEFSNRPHR NRPLLMSNGK SHKKKFVSWN CKQKLLDISL 300
FRNPFFYIFT WSFLLSQLAY FIPTFHLVAR AKTLGIDVMD ASYLVSVAGI TETVSQLISG 360
WIADQNWIKK YQYHKSYLIL CGVTNLLAPL ATTFPLLMAY TILFAIFAGG YLALILPVLV 420
DLSKNSRVHK FLGYASFFAG IAVLSGPPIA GWIYDYTQTY TGSFYFSGTC YILSSVSLFF 480
VPLAERWKRK QSDLLRTTIK 500 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0015293; F:symporter activity; IEA:UniProtKB-KW. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |