CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029250
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sodium/hydrogen exchanger 
Protein Synonyms/Alias
  
Gene Name
 Slc9a9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
617SSGQTPGKENIYEGDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Antiport; Ion transport; Membrane; Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 644 AA 
Protein Sequence
MAGQLRFTSG KDEDHFQHQG AVELLAFNFL LILTILTIWL FKNHRFRFLH ETGGAMVYGL 60
IMGLILRYAT APTDIDSGTV YNCGNLFFSP STLLVNITDQ VYEYKYQREI NQHNISPHQG 120
NAILEKMTFD PEIFFNVLLP PIIFHAGYSL KKRHFFQNLG SILTYAFLGT AISCVVIGLI 180
MYGFVKAMVH AGQLKSGDFH FTDCLFFGSL MSATDPVTVL AIFHELHVDP DLYTLLFGES 240
VLNDAVAIVL TYSISIYSPK ENPNAFDTAA FFQSVGNFLG IFAGSFAMGS AYAVVTALLT 300
KFTKLREFPM LETGLFFLLS WSAFLSAEAA GLTGIVAVLF CGVTQAHYTY NNLSSDSKLR 360
TKQLFEFMNF LAENVIFCYM GLALITFQNH IFNALFILGA FLAIFVARAC NIYPLSFLLN 420
LGRKQKIPWN FQHMMMFSGL RGAIAFALAI RNTESQPKQM MFTTTLLLVF FTVWVFGGGT 480
TPMLTWLQIR VGVDLDESLK EEPSSQQEAN KLDKNMTKTE SAQLFRMWYG FDHKYLKPIL 540
THSGPPLTTT LPAWCGPVSR LLTSPQAYGE QLKEDDVECI VNQDELAMNY QEQSPSPSSP 600
TTKLALDQKS SGQTPGKENI YEGDLGLGGY DLKLEQTRGQ PQMD 644 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
 GO:0006885; P:regulation of pH; IEA:InterPro. 
Interpro
 IPR006153; Cation/H_exchanger.
 IPR018422; Cation/H_exchanger_CPA1.
 IPR002090; Na/H_exchanger_6.
 IPR004709; NaH_exchanger. 
Pfam
 PF00999; Na_H_Exchanger 
SMART
  
PROSITE
  
PRINTS
 PR01084; NAHEXCHNGR.
 PR01088; NAHEXCHNGR6.