| Tag | Content |
|---|
| CPLM ID | CPLM-021093 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Potassium voltage-gated channel subfamily H member 7 |
Protein Synonyms/Alias | Ether-a-go-go-related gene potassium channel 3; ERG-3; Eag-related protein 3; Ether-a-go-go-related protein 3; Voltage-gated potassium channel subunit Kv11.3 |
Gene Name | Kcnh7 |
Gene Synonyms/Alias | Erg3 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 28 | KFEGQNKKFIIANAR | ubiquitination | [1] | | 343 | TLNFSDVKTEKKNTS | ubiquitination | [1] | | 362 | DKTIIAPKVKERTHN | ubiquitination | [1] | | 817 | EMVHLYAKPGKSNAD | ubiquitination | [1] | | 884 | DSEGDTGKLRRRRLS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Pore-forming (alpha) subunit of voltage-gated potassium channel (By similarity). Channel properties may be modulated by cAMP and subunit assembly. |
Sequence Annotation | DOMAIN 41 70 PAS.
DOMAIN 92 144 PAC.
NP_BIND 745 862 cNMP.
MOTIF 627 632 Selectivity filter (By similarity).
CARBOHYD 600 600 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Ion channel; Ion transport; Membrane; Potassium; Potassium channel; Potassium transport; Reference proteome; Transmembrane; Transmembrane helix; Transport; Voltage-gated channel. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1195 AA |
Protein Sequence | MPVRRGHVAP QNTFLGTIIR KFEGQNKKFI IANARVQNCA IIYCNDGFCE MTGFSRPDVM 60
QKPCTCDFLH GPETKRHDIA QIAQALLGSE ERKVEVTYYH KNGSTFICNT HIIPVKNQEG 120
VAMMFIINFE YVTDEENAAT PERVNPILPV KTVNRKLFGF KFPGLRVLTY RKQSLPQEDP 180
DVVVIDSSKH SDDSVAMKHF KSPTKESCSP SEADDTKALI QPSQCSPLVN ISGPLDHSSP 240
KRQWDRLYPD MLQSSSQLTH SRSRESLCSI RRASSVHDIE GFSVHPKNIF RDRHASEDNG 300
RNVKGPFNHI KSSLLGSTSD SNLNKYSTIN KIPQLTLNFS DVKTEKKNTS PPSSDKTIIA 360
PKVKERTHNV TEKVTQVLSL GADVLPEYKL QTPRINKFTI LHYSPFKAVW DWLILLLVIY 420
TAIFTPYSAA FLLNDREEQK RRECGYSCSP LNVVDLIVDI MFIIDILINF RTTYVNQNEE 480
VVSDPAKIAI HYFKGWFLID MVAAIPFDLL IFGSGSDETT TLIGLLKTAR LLRLVRVARK 540
LDRYSEYGAA VLMLLMCIFA LIAHWLACIW YAIGNVERPY LTDKIGWLDS LGTQIGKRYN 600
DSDSSSGPSI KDKYVTALYF TFSSLTSVGF GNVSPNTNSE KIFSICVMLI GSLMYASIFG 660
NVSAIIQRLY SGTARYHMQM LRVKEFIRFH QIPNPLRQRL EEYFQHAWTY TNGIDMNMVL 720
KGFPECLQAD ICLHLNQTLL QNCKAFRGAS KGCLRALAMK FKTTHAPPGD TLVHCGDVLT 780
ALYFLSRGSI EILKDDIVVA ILGKNDIFGE MVHLYAKPGK SNADVRALTY CDLHKIQRED 840
LLEVLDMYPE FSDHFLTNLE LTFNLRHESA KSQSVNDSEG DTGKLRRRRL SFESEGEKDF 900
SKENSANDAD DSTDTIRRYQ SSKKHFEERK SRSSSFISSI DDEQKPLFLG TVDSTPRMVK 960
ATRLHGEETM PHSGRIHTEK RSHSCRDITD THSWEREPAR AQPEECSPSG LQRAAWGVSE 1020
TESDLTYGEV EQRLDLLQEQ LNRLESQMTT DIQAILQLLQ KQTTVVPPAY SMVTAGAEYQ 1080
RPILRLLRTS HPRASIKTDR SFSPSSQCPE FLDLEKSKLQ SKESLSSGRR LNTASEDNLT 1140
SLLKQDSDAS SELDPRQRKT YLHPIRHPSL PDSSLSTVGI LGLHRHVSDP GLPGK 1195 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005242; F:inward rectifier potassium channel activity; IEA:Compara. GO:0004871; F:signal transducer activity; IEA:InterPro. GO:0007623; P:circadian rhythm; IEA:Compara. GO:0051291; P:protein heterooligomerization; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |