Tag | Content |
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CPLM ID | CPLM-004993 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Proteasome subunit alpha type-4 |
Protein Synonyms/Alias | Macropain subunit C9; Multicatalytic endopeptidase complex subunit C9; Proteasome component C9; Proteasome subunit L |
Gene Name | Psma4 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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180 | SMLKQDYKEGEMTLK | acetylation | [1] | 205 | NKTMDVSKLSAEKVE | acetylation | [1] | 231 | VIRVLKQKEVEQLIK | acetylation | [1] | 238 | KEVEQLIKKHEEEEA | acetylation | [1] | 246 | KHEEEEAKAEREKKE | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. |
Sequence Annotation | MOD_RES 13 13 Phosphoserine (By similarity). MOD_RES 75 75 Phosphoserine (By similarity). MOD_RES 127 127 N6-acetyllysine (By similarity). MOD_RES 176 176 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Nucleus; Phosphoprotein; Protease; Proteasome; Reference proteome; Threonine protease. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 261 AA |
Protein Sequence | MSRRYDSRTT IFSPEGRLYQ VEYAMEAIGH AGTCLGILAN DGVLLAAERR NIHKLLDEVF 60 FSEKIYKLNE DMACSVAGIT SDANVLTNEL RLIAQRYLLQ YQEPIPCEQL VTALCDIKQA 120 YTQFGGKRPF GVSLLYIGWD KHYGFQLYQS DPSGNYGGWK ATCIGNNSAA AVSMLKQDYK 180 EGEMTLKSAL ALAVKVLNKT MDVSKLSAEK VEIATLTREN GKTVIRVLKQ KEVEQLIKKH 240 EEEEAKAERE KKEKEQREKD K 261 |
Gene Ontology | GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0005839; C:proteasome core complex; ISS:UniProtKB. GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |