| Tag | Content |
|---|
| CPLM ID | CPLM-013895 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Enolase |
Protein Synonyms/Alias | 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase |
Gene Name | eno |
Gene Synonyms/Alias | TTHA0002 |
Created Date | July 27, 2013 |
Organism | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) |
NCBI Taxa ID | 300852 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 252 | SELYRDGKYHLEGEG | acetylation | [1] |
|
Reference | [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus. Okanishi H, Kim K, Masui R, Kuramitsu S. J Proteome Res. 2013 Aug 1;. [ PMID: 23901841] |
Functional Description | Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity). |
Sequence Annotation | REGION 363 366 Substrate binding (By similarity).
ACT_SITE 204 204 Proton donor (By similarity).
ACT_SITE 336 336 Proton acceptor (By similarity).
METAL 241 241 Magnesium (By similarity).
METAL 284 284 Magnesium (By similarity).
METAL 311 311 Magnesium (By similarity).
BINDING 154 154 Substrate (By similarity).
BINDING 163 163 Substrate (By similarity).
BINDING 284 284 Substrate (By similarity).
BINDING 311 311 Substrate (By similarity).
BINDING 336 336 Substrate (covalent); in inhibited form
BINDING 387 387 Substrate (By similarity).
MOD_RES 278 278 Phosphotyrosine (By similarity). |
Keyword | Complete proteome; Cytoplasm; Glycolysis; Lyase; Magnesium; Metal-binding; Phosphoprotein; Reference proteome; Secreted. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 422 AA |
Protein Sequence | MTTIVGVRAR EVLDSRGFPT VEAEVELEGG ARGRAMVPSG ASTGTHEALE LRDGGKRYLG 60
KGVRRAVENV NERIAPELVG MDALDQEGVD RAMLELDGTP NKANLGANAV LAVSLAVARA 120
AAEALGLPLY RYLGGVQGVT LPVPLMNVIN GGKHADNRVD FQEFMLVPAG AGSFAEALRI 180
GAEVFHTLKA VLKEKGYSTN VGDEGGFAPD LRSNEEAVEL LLLAIERAGY TPGQEVSLAL 240
DPATSELYRD GKYHLEGEGK VLSSEEMVAF WEAWVEKYPI RSIEDGLAED DWEGWRLLTE 300
RLGGKVQLVG DDLFVTNPER LRAGIERGVA NAILVKVNQI GTLSETLEAI RLAQRSGYRA 360
VISHRSGETE DSFIADLAVA VNAGQIKTGS LSRSDRLAKY NQLLRIEEEL GRAARFLGYA 420
AF 422 |
Gene Ontology | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro. GO:0000287; F:magnesium ion binding; IEA:HAMAP. GO:0004634; F:phosphopyruvate hydratase activity; IEA:HAMAP. GO:0006096; P:glycolysis; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |