CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001657
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 682 
Protein Synonyms/Alias
  
Gene Name
 ZNF682 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
304HSHLTKHKTIHTGKKacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 4 75 KRAB.
 ZN_FING 173 195 C2H2-type 1.
 ZN_FING 201 223 C2H2-type 2.
 ZN_FING 229 251 C2H2-type 3.
 ZN_FING 257 279 C2H2-type 4.
 ZN_FING 285 307 C2H2-type 5.
 ZN_FING 313 335 C2H2-type 6.
 ZN_FING 341 363 C2H2-type 7.
 ZN_FING 369 391 C2H2-type 8.
 ZN_FING 397 419 C2H2-type 9.
 ZN_FING 425 447 C2H2-type 10.
 ZN_FING 453 475 C2H2-type 11; degenerate.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 498 AA 
Protein Sequence
MELLTFRDVT IEFSLEEWEF LNPAQQSLYR KVMLENYRNL VSLGLTVSKP ELISRLEQRQ 60
EPWNVKRHET IAKPPAMSSH YTEDLLPEQC MQDSFQKVIL RRYGSCGLED LHLRKDGENV 120
GECKDQKEIY NGLNQCLSTL PSKIFPYNKC VKVFSKSSNL NRENIRHTTE KLFKCMQCGK 180
VFKSHSGLSY HKIIHTEEKL CICEECGKTF KWFSYLTKHK RIHTGEKPYK CEECGKAFNW 240
CSSLTKHKRI HTGEKPYKCE ECGKAFHWCS PFVRHKKIHT GEKPYTCEDC GRAFNRHSHL 300
TKHKTIHTGK KPYKCKECGK AFNHCSLLTI HERTHTGEKP YKCEECGKAF NSSSILTEHK 360
VIHSGEKPYK CEKCDKVFKR FSYLTKHKRI HTGEKPYKCE ECGKAFNWSS ILTEHKRIHT 420
GEKPYNCEEC GKAFNRCSHL TRHKKIHTAV KRYKCEECGK AFKRCSHLNE HKRVQRGEKS 480
CKYKKCGEAF NHCSNLTT 498 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS