CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006225
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Endosomal protein P24B 
Protein Synonyms/Alias
 24 kDa endomembrane protein; Basic 24 kDa late endocytic intermediate component 
Gene Name
 EMP24 
Gene Synonyms/Alias
 YGL200C; G1271 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
76PERHEVLKTVRDTSHacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Constituent of COPII-coated endoplasmic reticulum- derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. 
Sequence Annotation
 DOMAIN 30 118 GOLD.  
Keyword
 Complete proteome; Direct protein sequencing; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane; Protein transport; Reference proteome; Signal; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 203 AA 
Protein Sequence
MASFATKFVI ACFLFFSASA HNVLLPAYGR RCFFEDLSKG DELSISFQFG DRNPQSSSQL 60
TGDFIIYGPE RHEVLKTVRD TSHGEITLSA PYKGHFQYCF LNENTGIETK DVTFNIHGVV 120
YVDLDDPNTN TLDSAVRKLS KLTREVKDEQ SYIVIRERTH RNTAESTNDR VKWWSIFQLG 180
VVIANSLFQI YYLRRFFEVT SLV 203 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:SGD.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0030134; C:ER to Golgi transport vesicle; IDA:SGD.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; ISS:SGD.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.
 GO:0006621; P:protein retention in ER lumen; IMP:SGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0016050; P:vesicle organization; IGI:SGD. 
Interpro
 IPR009038; GOLD. 
Pfam
 PF01105; EMP24_GP25L 
SMART
  
PROSITE
 PS50866; GOLD 
PRINTS