UniProt Accession

 B2R6S5_HUMAN; B2R6S5 

Genbank Protein ID

 AK312693; CH471059; CH471059 

Genbank Nucleotide ID

 BAG35572.1; EAX06869.1; EAX06871.1 

Protein Name

 Cytidylate kinase, isoform CRA_a 

Protein Synonyms/Alias

 cDNA, FLJ93091, Homo sapiens UMP-CMP kinase (UMP-CMPK), mRNA 

Gene Name

 CMPK 

Gene Synonyms/Alias

 hCG_1780368 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
58	QCARIVEKYGYTHLS	ubiquitination	[1]
75	ELLRDERKNPDSQYG	ubiquitination	[1]
87	QYGELIEKYIKEGKI	ubiquitination	[1, 2]
120	AANAQKNKFLIDGFP	ubiquitination	[1]
138	DNLQGWNKTMDGKAD	ubiquitination	[1]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Kinase; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 228 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0033862; F:UMP kinase activity; IEA:Compara.
 GO:0046705; P:CDP biosynthetic process; IEA:Compara.
 GO:0006240; P:dCDP biosynthetic process; IEA:Compara.
 GO:0006227; P:dUDP biosynthetic process; IEA:Compara.
 GO:0022602; P:ovulation cycle process; IEA:Compara.
 GO:0018963; P:phthalate metabolic process; IEA:Compara.
 GO:0006225; P:UDP biosynthetic process; IEA:Compara. 

Interpro

 IPR000850; Adenylate_kin.
 IPR027417; P-loop_NTPase.
 IPR006266; UMP_CMP_kinase. 

Pfam

 PF00406; ADK 

SMART

  

PROSITE

 PS00113; ADENYLATE_KINASE 

PRINTS

 PR00094; ADENYLTKNASE.